Historique
Article de Périodique
Electronic cigarette use and respiratory symptoms in the French population-based Constances cohort (2024)
Auteur(s) :
DELMAS, M. C. ;
PASQUEREAU, A. ;
RENUY, A. ;
BENEZET, L. ;
RIBET, C. L. ;
ZINS, M. ;
GUIGNARD, R. ;
PEREZ, T. ;
ROCHE, N. ;
LEYNAERT, B. N. D.
Année :
2024
Page(s) :
art. 107496
Langue(s) :
Anglais
Refs biblio. :
40
Domaine :
Tabac / Tobacco / e-cigarette
Discipline :
PAT (Pathologie organique / Organic pathology)
Thésaurus géographique
FRANCE
Thésaurus mots-clés
COHORTE
;
E-CIGARETTE
;
POUMON
;
APPAREIL RESPIRATOIRE
;
PATHOLOGIE ORGANIQUE
;
ASTHME
;
SYMPTOME
;
ADULTE
;
TABAC
;
PNEUMOPATHIE
;
FUMEUR
;
NON-FUMEUR
;
ANCIEN FUMEUR
Résumé :
Background: Knowledge about the consequences of electronic cigarette (EC) use on respiratory health is still limited. We aimed to assess whether EC use is associated with the occurrence of asthma symptoms and chronic bronchitis among the French adult population, with a specific focus on never combustible cigarettes (CC) smokers. We further investigated whether the association differed in men and women.
Methods: Constances is a population-based cohort of adults aged 18-69 years at inception. We analyzed baseline data collected in 136,276 participants recruited in 2015-2019. Associations of current and former EC use with respiratory symptoms (asthma symptom score and chronic bronchitis) were assessed, controlling for CC smoking, cannabis use, demographics, education and body mass index (BMI).
Results: Increased frequencies of respiratory symptoms were observed in both current and former EC users (for the asthma symptom score, adjusted mean score ratio (aMSR): 1.34 [95 % confidence interval: 1.28-1.41] and 1.39 [1.33-1.45], respectively; for chronic bronchitis, adjusted prevalence ratio (aPR): 1.27 [1.19-1.36] and 1.40 [1.32-1.48], respectively). Among never CC smokers, ever EC use was associated with an increased asthma symptom score in both men and women (aMSR = 1.44 [1.09-1.90] and 1.36 [1.01-1.83], respectively), and with a higher prevalence of chronic bronchitis only in women (aPR = 1.97 [1.27-3.05]).
Conclusion: EC use is associated with symptoms of asthma and chronic bronchitis, independently of CC smoking and cannabis use. The fact that these associations are observed among individuals who have never smoked tobacco adds further evidence of the deleterious effects of EC on respiratory health. [Author's abstract]
Highlights:
It is unclear whether electronic cigarettes have harmful effects on respiratory health.
We found that e-cig use was associated with more asthma symptoms in adults.
E-cig use was also associated with an increased risk of chronic bronchitis.
In never smokers, e-cig was associated with asthma, and with chronic bronchitis in women.
Methods: Constances is a population-based cohort of adults aged 18-69 years at inception. We analyzed baseline data collected in 136,276 participants recruited in 2015-2019. Associations of current and former EC use with respiratory symptoms (asthma symptom score and chronic bronchitis) were assessed, controlling for CC smoking, cannabis use, demographics, education and body mass index (BMI).
Results: Increased frequencies of respiratory symptoms were observed in both current and former EC users (for the asthma symptom score, adjusted mean score ratio (aMSR): 1.34 [95 % confidence interval: 1.28-1.41] and 1.39 [1.33-1.45], respectively; for chronic bronchitis, adjusted prevalence ratio (aPR): 1.27 [1.19-1.36] and 1.40 [1.32-1.48], respectively). Among never CC smokers, ever EC use was associated with an increased asthma symptom score in both men and women (aMSR = 1.44 [1.09-1.90] and 1.36 [1.01-1.83], respectively), and with a higher prevalence of chronic bronchitis only in women (aPR = 1.97 [1.27-3.05]).
Conclusion: EC use is associated with symptoms of asthma and chronic bronchitis, independently of CC smoking and cannabis use. The fact that these associations are observed among individuals who have never smoked tobacco adds further evidence of the deleterious effects of EC on respiratory health. [Author's abstract]
Highlights:
It is unclear whether electronic cigarettes have harmful effects on respiratory health.
We found that e-cig use was associated with more asthma symptoms in adults.
E-cig use was also associated with an increased risk of chronic bronchitis.
In never smokers, e-cig was associated with asthma, and with chronic bronchitis in women.
Affiliation :
Santé publique France, French National Public Health Agency, Saint-Maurice, France
Université de Paris Cité, Université Paris-Saclay, UVSQ, Inserm, Cohortes Epidémiologiques en population, Villejuif, France
CHU de Lille, Service de Pneumologie et Immuno-allergologie, Service d’Explorations Fonctionnelles Respiratoires, Université Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR9017-CIIL-Centre d'Infection et d'Immunité de Lille, Lille, France
APHP Centre - Université de Paris, Hôpital et Institut Cochin, Service de Pneumologie, Paris, France
Université Paris-Saclay, UVSQ, Université Paris-Sud, Inserm, Equipe d'Epidémiologie Respiratoire Intégrative, CESP, Villejuif, France
Université de Paris Cité, Université Paris-Saclay, UVSQ, Inserm, Cohortes Epidémiologiques en population, Villejuif, France
CHU de Lille, Service de Pneumologie et Immuno-allergologie, Service d’Explorations Fonctionnelles Respiratoires, Université Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR9017-CIIL-Centre d'Infection et d'Immunité de Lille, Lille, France
APHP Centre - Université de Paris, Hôpital et Institut Cochin, Service de Pneumologie, Paris, France
Université Paris-Saclay, UVSQ, Université Paris-Sud, Inserm, Equipe d'Epidémiologie Respiratoire Intégrative, CESP, Villejuif, France