Titre : | Drug consumption rooms are effective to reduce at-risk practices associated with HIV/HCV infections among people who inject drugs: Results from the COSINUS cohort study (2024) |
Auteurs : | L. LALANNE ; P. ROUX ; C. DONADILLE ; L. BRIAND MADRID ; I. CELERIER ; C. CHAUVIN ; N. HAMELIN ; C. KERVRAN ; G. MARADAN ; M. AURIACOMBE ; M. JAUFFRET-ROUSTIDE ; The Cosinus Study Group |
Type de document : | Article : Périodique |
Dans : | Addiction (Vol.119, n°1, January 2024) |
Article en page(s) : | 180-199 |
Langues: | Anglais |
Discipline : | MAL (Maladies infectieuses / Infectious diseases) |
Mots-clés : |
Thésaurus géographique FRANCEThésaurus mots-clés COHORTE ; SALLE DE CONSOMMATION A MOINDRE RISQUE ; REDUCTION DES RISQUES ET DES DOMMAGES ; VIH ; HEPATITE ; USAGER ; INJECTION ; ECHANGE DE SERINGUES ; CONDUITE A RISQUE ; ETUDE PROSPECTIVE ; PRODUIT ILLICITE ; DEPISTAGE ; TRAITEMENT DE MAINTENANCE |
Résumé : |
Aims: The primary aim of this study was to evaluate the impact of drug consumption rooms (DCRs) in France on injection equipment-sharing, while the secondary aims focused upon their impact on access to hepatitis C virus (HCV) testing and opioid agonist treatment (OAT).
Design: The COhort to identify Structural and INdividual factors associated with drug USe (COSINUS cohort) was a 12-month longitudinal study of 665 people who inject drugs (PWID), conducted in Bordeaux, Marseille, Paris and Strasbourg. We used data from face-to-face interviews at enrolment and at 6-month and 12-month visits. Setting and participants: The participants were recruited in harm reduction programmes in Bordeaux and Marseille and in DCRs in Strasbourg and Paris. Participants were aged more than 18 years, French-speaking and had injected substances the month before enrolment. Measurements: We measured the impact of DCR exposure on injection equipment sharing, HCV testing and the use of medications for opioid use disorder, after adjustment for significant correlates. We used a two-step Heckman mixed-effects probit model, which allowed us to take into account the correlation of repeated measures and to control for potential bias due to non-randomization between the two groups (DCR-exposed versus DCR-unexposed participants). Findings: The difference of declared injection equipment sharing between PWID exposed to DCRs versus non-exposed was 10% (1% for those exposed versus 11% for those non-exposed, marginal effect = -0.10; 95% confidence interval = -0.18, -0.03); there was no impact of DCRs on HCV testing and OAT. Conclusions: In the French context, drug consumption rooms appear to have a positive impact on at-risk practices for infectious diseases such as human immunodeficiency virus (HIV) and hepatitis C virus. |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 48 |
Affiliation : | Centre d'étude des Mouvements Sociaux (Inserm U1276/CNRS UMR8044/EHESS), Paris, France |
Cote : | Abonnement |
Lien : | https://doi.org/10.1111/add.16320 |
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