| Titre : | Prospective study of e-cigarette use and respiratory symptoms in adolescents and young adults (2023) |
| Auteurs : | A. P. TACKETT ; R. URMAN ; J. BARRINGTON-TRIMIS ; F. LIU ; H. HONG ; M. A. PENTZ ; T. S. ISLAM ; S. P. ECKEL ; M. REBULI ; A. LEVENTHAL ; J. M. SAMET ; K. BERHANE ; R. MCCONNELL |
| Type de document : | Article : Périodique |
| Dans : | Thorax (Online first 15/08/2023, 2023) |
| Article en page(s) : | doi : 10. 1136/ thorax- 2022- 218670 |
| Langues: | Anglais |
| Discipline : | PAT (Pathologie organique / Organic pathology) |
| Mots-clés : |
Thésaurus géographique ETATS-UNISThésaurus mots-clés ETUDE PROSPECTIVE ; E-CIGARETTE ; FACTEUR DE RISQUE ; SYMPTOME ; ADOLESCENT ; JEUNE ADULTE ; APPAREIL RESPIRATOIRE |
| Résumé : |
RATIONALE: Electronic cigarette (e-cigarette) aerosol contains volatile aldehydes, including flavourings and oxidant metals with known pulmonary toxicity.
OBJECTIVES: To evaluate the associations of e-cigarette use with symptoms of wheeze, bronchitic symptoms and shortness of breath (SOB) across 4 years of prospective data. METHODS: Participants completed questionnaires on respiratory symptoms and past 30-day e-cigarette, cigarette and cannabis use in 2014 (wave 1; N=2094; mean age 17.3 years, SD=0.6 years). Follow-up information was collected in 2015 (wave 2; n=1609), 2017 (wave 3; n=1502) and 2018 (wave 4; n=1637) using online surveys. Mixed-effects logistic regression models evaluated associations of e-cigarette use with respiratory symptoms. MEASUREMENTS AND MAIN RESULTS: Participants were mostly Hispanic white (51.8%) and evenly representative by sex (49.6% female; 50.4% male). Compared with never e-cigarette users, past 30-day e-cigarette users reported increased odds of wheeze (OR 1.95; 95% CI 1.39, 2.72), bronchitic symptoms (OR 2.10; 95% CI 1.61, 2.73) and SOB (OR 1.81; 95% CI 1.25, 2.60), adjusting for study wave, age, sex, race, lifetime asthma diagnosis and parental education. Effect estimates were attenuated (wheeze (OR 1.48; 95% CI 1.05, 2.09), bronchitic symptoms (OR 1.58; 95% CI 1.20, 2.07), SOB (OR 1.52; 95% CI 1.04, 2.22)), after adjusting additionally for current cigarette use, cannabis use and secondhand exposure to e-cigarettes/cigarettes/cannabis. CONCLUSIONS: E-cigarette use in young adults was associated with respiratory symptoms, independent of combustible cannabis and cigarette exposures. |
| Domaine : | Tabac / Tobacco |
| Refs biblio. : | 39 |
| Affiliation : | Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, California, USA |
| Lien : | https://doi.org/10.1136/thorax-2022-218670 |
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