Historique
Article de Périodique
Prospective study of e-cigarette use and respiratory symptoms in adolescents and young adults (2024)
Auteur(s) :
A. P. TACKETT ;
R. URMAN ;
J. BARRINGTON-TRIMIS ;
F. LIU ;
H. HONG ;
M. A. PENTZ ;
T. S. ISLAM ;
S. P. ECKEL ;
M. REBULI ;
A. LEVENTHAL ;
J. M. SAMET ;
K. BERHANE ;
R. MCCONNELL
Article en page(s) :
163-168
Refs biblio. :
39
Domaine :
Tabac / Tobacco / e-cigarette
Langue(s) :
Anglais
Discipline :
PAT (Pathologie organique / Organic pathology)
Thésaurus géographique
ETATS-UNIS
Thésaurus mots-clés
ETUDE PROSPECTIVE
;
E-CIGARETTE
;
FACTEUR DE RISQUE
;
SYMPTOME
;
ADOLESCENT
;
JEUNE ADULTE
;
APPAREIL RESPIRATOIRE
Résumé :
RATIONALE: Electronic cigarette (e-cigarette) aerosol contains volatile aldehydes, including flavourings and oxidant metals with known pulmonary toxicity.
OBJECTIVES: To evaluate the associations of e-cigarette use with symptoms of wheeze, bronchitic symptoms and shortness of breath (SOB) across 4 years of prospective data.
METHODS: Participants completed questionnaires on respiratory symptoms and past 30-day e-cigarette, cigarette and cannabis use in 2014 (wave 1; N=2094; mean age 17.3 years, SD=0.6 years). Follow-up information was collected in 2015 (wave 2; n=1609), 2017 (wave 3; n=1502) and 2018 (wave 4; n=1637) using online surveys. Mixed-effects logistic regression models evaluated associations of e-cigarette use with respiratory symptoms.
MEASUREMENTS AND MAIN RESULTS: Participants were mostly Hispanic white (51.8%) and evenly representative by sex (49.6% female; 50.4% male). Compared with never e-cigarette users, past 30-day e-cigarette users reported increased odds of wheeze (OR 1.95; 95% CI 1.39, 2.72), bronchitic symptoms (OR 2.10; 95% CI 1.61, 2.73) and SOB (OR 1.81; 95% CI 1.25, 2.60), adjusting for study wave, age, sex, race, lifetime asthma diagnosis and parental education. Effect estimates were attenuated (wheeze (OR 1.48; 95% CI 1.05, 2.09), bronchitic symptoms (OR 1.58; 95% CI 1.20, 2.07), SOB (OR 1.52; 95% CI 1.04, 2.22)), after adjusting additionally for current cigarette use, cannabis use and secondhand exposure to e-cigarettes/cigarettes/cannabis.
CONCLUSIONS: E-cigarette use in young adults was associated with respiratory symptoms, independent of combustible cannabis and cigarette exposures.
OBJECTIVES: To evaluate the associations of e-cigarette use with symptoms of wheeze, bronchitic symptoms and shortness of breath (SOB) across 4 years of prospective data.
METHODS: Participants completed questionnaires on respiratory symptoms and past 30-day e-cigarette, cigarette and cannabis use in 2014 (wave 1; N=2094; mean age 17.3 years, SD=0.6 years). Follow-up information was collected in 2015 (wave 2; n=1609), 2017 (wave 3; n=1502) and 2018 (wave 4; n=1637) using online surveys. Mixed-effects logistic regression models evaluated associations of e-cigarette use with respiratory symptoms.
MEASUREMENTS AND MAIN RESULTS: Participants were mostly Hispanic white (51.8%) and evenly representative by sex (49.6% female; 50.4% male). Compared with never e-cigarette users, past 30-day e-cigarette users reported increased odds of wheeze (OR 1.95; 95% CI 1.39, 2.72), bronchitic symptoms (OR 2.10; 95% CI 1.61, 2.73) and SOB (OR 1.81; 95% CI 1.25, 2.60), adjusting for study wave, age, sex, race, lifetime asthma diagnosis and parental education. Effect estimates were attenuated (wheeze (OR 1.48; 95% CI 1.05, 2.09), bronchitic symptoms (OR 1.58; 95% CI 1.20, 2.07), SOB (OR 1.52; 95% CI 1.04, 2.22)), after adjusting additionally for current cigarette use, cannabis use and secondhand exposure to e-cigarettes/cigarettes/cannabis.
CONCLUSIONS: E-cigarette use in young adults was associated with respiratory symptoms, independent of combustible cannabis and cigarette exposures.
Affiliation :
Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, California, USA