| Titre : | Suitability of high-resolution mass spectrometry in analytical toxicology: Focus on drugs of abuse (2022) |
| Auteurs : | R. GONCALVES ; R. PELLETIER ; A. COUETTE ; T. GICQUEL ; B. LE DARE |
| Type de document : | Article : Périodique |
| Dans : | Toxicologie Analytique et Clinique (Vol.34, n°1 Suppl., Janvier 2022) |
| Article en page(s) : | 29-41 |
| Langues: | Anglais |
| Discipline : | PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods) |
| Mots-clés : |
Thésaurus mots-clés TOXICOLOGIE ; ANALYSE CHIMIQUE ; DROGUES DE SYNTHESE ; METABOLISME ; DEPISTAGE ; METHODE ; MESURES QUANTITATIVES ; MESURES QUALITATIVES ; BASE DE DONNEES |
| Résumé : | High-resolution mass spectrometry (HRMS) is now the method of choice in several toxicology contexts. This paper reviews HRMS approaches for research and application in various toxicology fields, focusing on drugs of abuse in clinical and forensic toxicology. Papers concerning HRMS applications in screening, quantification and metabolism of drugs of abuse in biological and non-biological samples were included. Specific applications for new psychoactive substances in contexts such as online libraries, bioinformatic tools (molecular networking) and methods combinations were also included. |
| Domaine : | Drogues illicites / Illicit drugs |
| Sous-type de document : | Revue de la littérature / Literature review |
| Refs biblio. : | 112 |
| Affiliation : | Forensic and Clinical Toxicology Laboratory, CHU de Bordeaux, Bordeaux, France |
| Cote : | Abonnement |
| Lien : | https://doi.org/10.1016/j.toxac.2021.11.006 |
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