Titre : | Potency of Delta9-tetrahydrocannabinol and other cannabinoids in cannabis in England in 2016: Implications for public health and pharmacology (2018) |
Auteurs : | D. J. POTTER ; K. HAMMOND ; S. TUFFNELL ; C. WALKER ; M. DI FORTI |
Type de document : | Article : Périodique |
Dans : | Drug Testing and Analysis (Vol.10, n°4, April 2018) |
Article en page(s) : | 628-635 |
Langues: | Anglais |
Discipline : | PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods) |
Mots-clés : |
Thésaurus géographique ANGLETERRE ; ROYAUME-UNIThésaurus mots-clés CANNABINOIDES ; TETRAHYDROCANNABINOL ; CANNABIS ; ANALYSE CHIMIQUE ; PHARMACOLOGIE ; SANTE MENTALE |
Résumé : | In 2005 and 2008, studies reported that cannabis in England had become dominated by the sinsemilla (unseeded female) form. The average potency (Delta9-tetrahydrocannabinol [THC] content) of this material had doubled over the previous decade. Cannabis resin then circulating contained approximately equal ratios of THC and cannabidiol (CBD), whereas sinsemilla was almost devoid of CBD. Despite raised health concerns regarding sinsemilla use and the development of psychotic disorders, no update on street cannabis potency has been published since 2008. A total of 995 seized cannabis samples were acquired from the same 5 constabulary areas included in the 2005 study. The differing forms were segregated, and a representative 460 samples analyzed to assess their cannabinoid content using gas chromatography. The resultant median sinsemilla potency of 14.2% THC was similar to that observed in 2005 (13.9%). In each case, sinsemilla contained minimal CBD. Compared with 2005, resin had significantly higher mean THC (6.3%) and lower CBD (2.3%) contents (p |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 39 |
Affiliation : | GW Pharmaceuticals plc, Cambridge, UK |
Cote : | Abonnement |
URL : | https://theconversation.com/nearly-all-cannabis-seized-by-uk-police-is-high-strength-skunk-heres-why-we-should-be-worried-92489 |
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