|Titre :||Associations between cigarette smoking and cannabis dependence: A longitudinal study of young cannabis users in the United Kingdom (2015)|
|Auteurs :||C. HINDOCHA ; N. D. C. SHABAN ; T. P. FREEMAN ; R. K. DAS ; G. GALE ; G. SCHAFER ; C. J. FALCONER ; C. J. A. MORGAN ; H. V. CURRAN|
|Type de document :||Article : Périodique|
|Dans :||Drug and Alcohol Dependence (Vol.148, March 2015)|
|Article en page(s) :||165-171|
|Discipline :||EPI (Epidémiologie / Epidemiology)|
Thésaurus TOXIBASETABAC ; CANNABIS ; DEPENDANCE ; ETUDE LONGITUDINALE ; ADOLESCENT ; ADULTE JEUNE ; COMORBIDITE ; FACTEUR PREDICTIF ; POLYCONSOMMATION ; MODELE
Aims: To determine the degree to which cigarette smoking predicts levels of cannabis dependence above and beyond cannabis use itself, concurrently and in an exploratory four-year follow-up, and to investigate whether cigarette smoking mediates the relationship between cannabis use and cannabis dependence.
Methods: The study was cross sectional with an exploratory follow-up in the participants’ own homes or via telephone interviews in the United Kingdom. Participants were 298 cannabis and tobacco users aged between 16 and 23; follow-up consisted of 65 cannabis and tobacco users. The primary outcome variable was cannabis dependence as measured by the Severity of Dependence Scale (SDS). Cannabis and tobacco smoking were assessed through a self-reported drug history.
Results: Regression analyses at baseline showed cigarette smoking (frequency of cigarette smoking: B = 0.029, 95% CI = 0.01, 0.05; years of cigarette smoking: B = 0.159, 95% CI = 0.05, 0.27) accounted for 29% of the variance in cannabis dependence when controlling for frequency of cannabis use. At follow-up, only baseline cannabis dependence predicted follow-up cannabis dependence (B = 0.274, 95% CI = 0.05, 0.53). At baseline, cigarette smoking mediated the relationship between frequency of cannabis use and dependence (B = 0.0168, 95% CI = 0.008, 0.288) even when controlling for possible confounding variables (B = 0.0153, 95% CI = 0.007, 0.027).
Conclusions: Cigarette smoking is related to concurrent cannabis dependence independently of cannabis use frequency. Cigarette smoking also mediates the relationship between cannabis use and cannabis dependence suggesting tobacco is a partial driver of cannabis dependence in young people who use cannabis and tobacco.
- We studied the extent that cigarette smoking predicts level of cannabis addiction.
- We tested whether cigarette smoking mediates the effect of cannabis use on dependence.
- We interviewed 298 cannabis and tobacco users, of which 65 were followed up.
- Cigarette smoking accounted for 29% of the variance in cannabis dependence.
- Cigarette smoking mediated the relationship between cannabis use and dependence.
|Domaine :||Drogues illicites / Illicit drugs ; Tabac / Tobacco|
|Affiliation :||Clinical Psychopharmacology Unit, University College London, Gower Street, London, UK|