Titre : | Amphetamine-group substances and HIV. HIV in people who use drugs 5 (2010) |
Auteurs : | COLFAX G. ; G. M. SANTOS ; P. CHU ; E. VITTINGHOFF ; PLUDDEMANN A. ; S. KUMAR ; C. HART |
Type de document : | Article : Périodique |
Dans : | Lancet (The) (Vol.376, n°9739, Aug 07, 2010) |
Article en page(s) : | 458-474 (Online 20 July) |
Langues: | Anglais |
Discipline : | MAL (Maladies infectieuses / Infectious diseases) |
Mots-clés : |
Thésaurus mots-clés AMPHETAMINES ; THERAPIE COMPORTEMENTALE ; INTERVENTION ; PHARMACOTHERAPIE |
Résumé : | Amphetamine-group substances are used worldwide and are more prevalent than either cocaine or opioids. We reviewed published reports about amphetamine-group substances and did a meta-analysis of randomised controlled trials of behavioural interventions for their use. Most research was done in developed countries. Many, but not all, studies show an association between amphetamine-group substance use and risk of HIV infection. Much use of amphetamine-group substances is non-injection and is associated with increased HIV risk, particularly in men who have sex with men. The structural, social, interpersonal, and personal factors that link to amphetamine-group substance use and HIV risk are poorly understood. 13 studies, with a cumulative sample size of 1997 individuals, qualified for the meta-analysis. Overall, high-intensity behavioural interventions were moderately effective in reducing use of amphetamine-group substances (effect size 0.28, 95% CI 0.13-0.44). We did not find conclusive evidence that behavioural interventions as a group are more effective than are passive or minium treatment for reduction of amphetamine-group substance use or sexual risk behaviours. The search for effective, scalable, and sustainable interventions for amphetamine-group substance use, including pharmacotherapies, should be supported and encouraged. [Author's abstract] |
Domaine : | Drogues illicites / Illicit drugs |
Sous-type de document : | Revue de la littérature / Literature review |
Refs biblio. : | 143 |
Affiliation : | HIV Prevention Section, San Francisco Department of Public Health, San Francisco, CA ; University of California, San Francisco, CA, United States / Etats-Unis |
Lien : | http://www.thelancet.com/series/hiv-in-people-who-use-drugs |
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