Titre : | Benzodiazepine abuse in a methadone maintenance treatment clinic in Israel: characteristics and a pharmacotherapeutic approach |
Titre traduit : | (Abus de benzodiazépines dans une clinique israélienne de traitement de maintenance à la méthadone : caractéristiques et approche pharmaco-thérapeutique) |
Auteurs : | BLEICH A. ; GELKOPF M. ; WEIZMAN T. ; M. ADELSON |
Type de document : | Périodique |
Année de publication : | 2002 |
Format : | 104-112 / tabl. |
Note générale : |
Israel Journal of Psychiatry and Related Sciences, 2002, 39, (2), 104-112 |
Langues: | Français |
Discipline : | EPI (Epidémiologie / Epidemiology) |
Mots-clés : |
Thésaurus mots-clés BENZODIAZEPINES ; TRAITEMENT DE MAINTENANCE ; ABUS ; POLYCONSOMMATION ; ENQUETE ; PREVENTION ; MESURES QUANTITATIVES ; METHADONEThésaurus géographique ISRAEL |
Résumé : |
ENGLISH : OBJECTIVE: 1) To study the prevalence, course and correlates of benzodiazepine (BZD) abuse in an Israeli methadone maintenance treatment (MMT) clinic; and 2) to present preliminary results of an open clinical study on the treatment of BZD addiction in MMT patients using BZD maintenance. METHODS: Study 1 was carried out on 196 patients who were in MMT for at least one year. Objective information on drug use (urine testing) was recorded, and the one-year retention rate was measured. Demographic data and history of abuse were obtained, and a self-rated psychopathology and psychological distress questionnaire was administered. The second study was an open one. Twenty BZD-addicted patients were given clonazepam maintenance treatment (CMT) and were started on a daily regimen of 6 mg. followed by a gradual tapering until an individual dose was reached. This maintenance dose was the lowest level at which the patient still expressed satisfaction with the BZD dose without reporting craving or overdose. Failure was defined by three daily consecutive BZD uses above the permitted dose. RESULTS: BZD abuse was significantly reduced during the first year of MMT (from 55 to 43%, P |
Note de contenu : | tabl. |
Domaine : | Autres substances / Other substances |
Refs biblio. : | 28 |
Affiliation : |
Dr Miriam and Sheldon G. Adelson Clinic for Drug Abuse Treatment and Research, Tel Aviv Israël. Israel. |
Numéro Toxibase : | 1300576 |
Centre Emetteur : | 13 OFDT |
Cote : | A01306 |
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