Titre : | Causal association between cannabis and psychosis: examination of the evidence (2004) |
Titre traduit : | (Relation causale entre cannabis et psychose : observation des faits) |
Auteurs : | L. ARSENEAULT ; M. CANNON ; J. WITTON ; R. M. MURRAY |
Type de document : | Article : Périodique |
Dans : | British Journal of Psychiatry (Vol.184, n°2, February 2004) |
Article en page(s) : | 110-117 |
Langues: | Anglais |
Discipline : | PSY (Psychopathologie / Psychopathology) |
Mots-clés : |
Thésaurus mots-clés CANNABIS ; TROUBLE BIPOLAIRE ; PSYCHOSE ; FACTEUR DE RISQUE ; ENQUETE ; EPIDEMIOLOGIEThésaurus géographique SUEDE ; PAYS-BAS ; NOUVELLE ZELANDE |
Résumé : |
BACKGROUND: Controversy remains as to whether cannabis acts as a causal risk factor for schizophrenia or other functional psychotic illnesses.
AIMS: To examine critically the evidence that cannabis causes psychosis using established criteria of causality. METHOD: We identified five studies that included a well-defined sample drawn from population-based registers or cohorts and used prospective measures of cannabis use and adult psychosis. RESULTS: On an individual level, cannabis use confers an overall twofold increase in the relative risk for later schizophrenia. At the population level, elimination of cannabis use would reduce the incidence of schizophrenia by approximately 8%, assuming a causal relationship. Cannabis use appears to be neither a sufficient nor a necessary cause for psychosis. It is a component cause, part of a complex constellation of factors leading to psychosis. CONCLUSIONS: Cases of psychotic disorder could be prevented by discouraging cannabis use among vulnerable youths. Research is needed to understand the mechanisms by which cannabis causes psychosis. (Review' s abstract) |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 44 |
Affiliation : | Institute of Psychiatry, De Crespigny Park, London, UK |
Numéro Toxibase : | 1300873 |
Centre Emetteur : | 13 OFDT |
Cote : | A01648 |
Lien : | http://dx.doi.org/10.1192/bjp.184.2.110 |
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