Historique
Article de Périodique
Neurological and psychopathological sequelae associated with a lifetime intake of 40,000 ecstasy tablets [Letter] (2006)
Auteur(s) :
KOUIMTSIDIS C. ;
SCHIFANO, F. ;
SHARP, T. ;
FORD, L. ;
ROBINSON, J. ;
MAGEE C.
Année :
2006
Page(s) :
86-87
Langue(s) :
Anglais
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PSY (Psychopathologie / Psychopathology)
Thésaurus mots-clés
MDMA-ECSTASY
;
USAGE REGULIER
;
ABUS
;
PSYCHOPATHOLOGIE
;
NEUROLOGIE
;
ETUDE DE CAS
;
SEXE MASCULIN
;
TROUBLES DE LA MEMOIRE
Thésaurus géographique
ROYAUME-UNI
Note générale :
Editorial: The Lancet 2006;367(9518):1214, "Reviving research into psychedelic drugs".
Résumé :
TO THE EDITOR: The medical and psychopathological consequences of both acute and chronic "ecstasy" (MDMA, MDA, and derivatives) consumption have been extensively described, but little is known with respect to the relationship between both severity and persistence of these disturbances and lifetime number of ecstasy tablets ingested. At-risk MDMA intake seems to be related to long-term functional dysregulation in 5-HT2 pathways, resulting in altered regulation of mood, impulse control, and memory. Ecstasy consumption has spread since the late 80s, and the reduction in price observed over the last few years has possibly increased access to the drug. Clinicians are now meeting with a generation of patients who have been exposed to the drug for more than a decade. In this report, we describe both the transient and persisting sequelae associated with an unusual amount of ecstasy consumption.
Affiliation :
University of London, UK
Cote :
A02664