| Titre : | Hepatitis C virus reinfection in injection drug users |
| Titre traduit : | (La réinfection par le virus de l'hépatite C chez les usagers de drogues par injection) |
| Auteurs : | J. GREBELY ; B. CONWAY ; RAFFA J. D. ; C. LAI ; M. KRAJDEN ; M. W. TYNDALL |
| Type de document : | Périodique |
| Année de publication : | 2006 |
| Format : | 1139-1145 |
| Note générale : |
Hepatology, 2006, 44, (5), 1139-1145 |
| Langues: | Français |
| Discipline : | MAL (Maladies infectieuses / Infectious diseases) |
| Mots-clés : |
Thésaurus mots-clés HEPATITE ; INFECTION ; INJECTION ; FACTEUR DE RISQUE ; COHORTEThésaurus géographique CANADA |
| Résumé : |
ENGLISH : Spontaneous clearance of hepatitis C (HCV) may provide protection against reinfection. In a large community-based cohort study of 3,553 inner-city residents (mainly injection drug users), we identified HCV-infected individuals in whom virological clearance had occurred and compared the rate of reinfection in this group with that observed in previously uninfected members of the same cohort. We identified 926 HCV-uninfected and 658 HCV-infected viremic subjects at baseline, with 152 of 658 (23.1%) spontaneously clearing viremia over a median follow-up of 5.2 years (IQR, 2.8-7.4). At baseline, individuals with HCV clearance were more likely to be HIV coinfected (P |
| Domaine : | Drogues illicites / Illicit drugs |
| Refs biblio. : | 30 |
| Affiliation : |
Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC. Email : jgrebely@interchange.ubc.ca Canada. Canada. |
| Centre Emetteur : | 13 OFDT |
| Cote : | A02979 |
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