| Titre : | Recreational drug use and the risk of primary infertility |
| Titre traduit : | (Usage récréatif de drogue et risque d'infertilité.) |
| Auteurs : | B. A. MUELLER ; DALING J. R. ; N. S. WEISS ; D. E. MOORE |
| Type de document : | Périodique |
| Année de publication : | 1990 |
| Format : | 195-200 |
| Note générale : |
Epidemiology, 1990, 1, (3), 195-200 |
| Langues: | Anglais |
| Mots-clés : |
Thésaurus mots-clés CANNABIS ; USAGE RECREATIF ; SEXE FEMININ ; STERILITE ; REPRODUCTION ; FACTEUR DE RISQUE ; LSD ; COCAINE ; AMPHETAMINESThésaurus géographique ETATS-UNIS |
| Résumé : |
ENGLISH : Recreational drug (marijuana, lysergic acid diethylamide or LSD, speed, cocaine, and "other") exposures of women with primary infertility were compared with those of a matched control group of women with proven fertility. Women who reported smoking marijuana had a slightly elevated risk for infertility due to an ovulatory abnormality (RR = 1.7, 95% CI = 1.0 to 3.0). The risk was greatest among women who had used marijuana within one year of trying to become pregnant (RR = 2.1, 95% CI = 1.1 to 4.0). No consistent frequency or duration of use effects could be demonstrated, and the risk was confined to low-frequency users. Risks associated with the use of other drugs were not elevated. The risk of infertility from a tubal abnormality associated with cocaine use was greatly increased (RR = 11.1, 95% CI = 1.7 to 70.8). Our results are consistent with animal studies suggesting that smoking marijuana may cause a transient disruption of ovulatory function. The possibility that cocaine exposure influences the development of tubal infertility needs further investigation. (Author' s abstract) |
| Domaine : | Drogues illicites / Illicit drugs |
| Refs biblio. : | 12 |
| Affiliation : |
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98104 Etats-Unis. United States. |
| Centre Emetteur : | 13 OFDT |
| Cote : | A03148 |
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