Titre : | Drug use and medication adherence among HIV-1 infected individuals |
Titre traduit : | (Usage de drogue et compliance chez des individus infectés par le VIH-1.) |
Auteurs : | C. H. HINKIN ; T. R. BARCLAY ; S. A. CASTELLON ; A. J. LEVINE ; DURVASULA R. S. ; S. D. MARION ; H. F. MYERS ; D. LONGSHORE |
Type de document : | Périodique |
Année de publication : | 2007 |
Format : | 185-194 |
Note générale : |
AIDS and Behavior, 2007, 11, (2), 185-194 |
Langues: | Français |
Discipline : | MAL (Maladies infectieuses / Infectious diseases) |
Mots-clés : |
Thésaurus mots-clés VIH ; INFECTION ; SIDA ; OBSERVANCE DU TRAITEMENT ; METHAMPHETAMINE ; COCAINE ; ETUDE LONGITUDINALEThésaurus géographique ETATS-UNIS |
Résumé : |
ENGLISH : This longitudinal study examined the impact of drug use and abuse on medication adherence among 150 HIV-infected individuals, 102 who tested urinalysis positive for recent illicit drug use. Medication adherence was tracked over a 6-month period using an electronic monitoring device (MEMS caps). Over the 6-month study drug-positive participants demonstrated significantly worse medication adherence than did drug-negative participants (63 vs. 79%, respectively). Logistic regression revealed that drug use was associated with over a fourfold greater risk of adherence failure. Stimulant users were at greatest risk for poor adherence. Based upon within-participants analyses comparing 3-day adherence rates when actively using versus not using drugs, this appears to be more a function of state rather than trait. These data suggest that it is the acute effects of intoxication, rather than stable features that may be characteristic of the drug-using populace, which leads to difficulties with medication adherence. (Author' s abstract) |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 58 |
Affiliation : |
David Geffen School of Medicine, University of California at Los Angeles, 760 Westwood Plaza, Room C8-747, Los Angeles, CA 90024. Email : chinkin@ucla.edu Etats-Unis. United States. |
Centre Emetteur : | 13 OFDT |
Cote : | A03195 |
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