Périodique
Trace elements in drug addicts
(Oligoéléments chez les toxicomanes)
Auteur(s) :
RUIZ MARTINEZ, M. ;
GIL EXTREMERA, B. ;
MALDONADO MARTIN, A. ;
CANTERO-HINOJOSA J. ;
MORENO ABADIA, V.
Année :
1990
Langue(s) :
Anglais
ISBN :
0023-2173
Refs biblio. :
28
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Note générale :
Klinische Wochenschrift, 1990, 68(10), 507-511
Résumé :
FRANÇAIS :
Le dosage d'oligo-éléments sur 100 drogués et 20 témoins montre chez les drogués une diminution du zinc et du fer, due à la toxicité des drogues ou à une carence et sans rapport avec les infections virales de ce groupe.
ENGLISH :
We studied trace elements (zinc, copper, magnesium, iron and lithium) by atomic absorption spectrophotometry in the plasma and erythrocytes of 120 subjects : 20 healthy controls and 100 parenteral drug addicts (69 heroin and 31 heroin + other drugs). Plasma Zn and intraerythrocytic Zn and Fe were decreased, whereas plasma and intraerythrocytic Cu were significantly increased in the group of drug addicts with respect to the healthy controls. Moreover, a period of abstinence longer than 10 days was associated with lower plasma levels of Zn and Li in subjects who had taken drugs shortly before they were examined. The presence of serological markers against HBV and HIV did not seem to influence the behavior of the trace elements in blood. (Author's abstract).
Le dosage d'oligo-éléments sur 100 drogués et 20 témoins montre chez les drogués une diminution du zinc et du fer, due à la toxicité des drogues ou à une carence et sans rapport avec les infections virales de ce groupe.
ENGLISH :
We studied trace elements (zinc, copper, magnesium, iron and lithium) by atomic absorption spectrophotometry in the plasma and erythrocytes of 120 subjects : 20 healthy controls and 100 parenteral drug addicts (69 heroin and 31 heroin + other drugs). Plasma Zn and intraerythrocytic Zn and Fe were decreased, whereas plasma and intraerythrocytic Cu were significantly increased in the group of drug addicts with respect to the healthy controls. Moreover, a period of abstinence longer than 10 days was associated with lower plasma levels of Zn and Li in subjects who had taken drugs shortly before they were examined. The presence of serological markers against HBV and HIV did not seem to influence the behavior of the trace elements in blood. (Author's abstract).
Affiliation :
Dept Med. Fac. Med., ave Madrid s / n, 18071 Granada
Espagne. Spain.
Espagne. Spain.