Historique
Périodique
Concurrent substance use and outcome in combined behavioral and naltrexone therapy for opiate dependence
(Usage concomitant de drogue lors d'un traitement combiné par thérapie comportementale et naltrexone de la dépendance aux opiacés)
Auteur(s) :
S. H. CHURCH ;
J. L. ROTHENBERG ;
M. A. SULLIVAN ;
G. BORNSTEIN ;
E. V. NUNES
Article en page(s) :
441-452
Domaine :
Drogues illicites / Illicit drugs
Langue(s) :
Anglais
Thésaurus mots-clés
OPIACES
;
TRAITEMENT AMBULATOIRE
;
THERAPIE COMPORTEMENTALE
;
NALTREXONE
;
CONSOMMATION
;
COCAINE
;
CANNABIS
;
BENZODIAZEPINES
Note générale :
American Journal of Drug and Alcohol Abuse (The), 2001, 27, (3), 441-452
Résumé :
The effect of concurrent nonopiate drug use on outcome of treatment for opiate dependence, Method: Forty-seven opiate-dependent patients received a 6-month course of outpatient treatment with naltrexone and cognitive-behavioral therapy (behavioral naltrexone therapy, BNT) at a university-based research clinic. Opiate-negative urines and naltrexone ingestion were rewarded with monetary vouchers. Abstinence from other drugs was encouraged verbally, but no contingencies were placed on nonopiate drug use. The proportions of all urines (collected twice weekly) positive for cocaine, cannabis, and benzodiazepines over the course of treatment were evaluated as predictors of outcome of opiate dependence treatment, as measured by proportion of opiate-positive urines, days retained in treatment, and proportion of naltrexone doses taken, using Pearson product moment correlations and one way analysis of variance (ANOVA). Results: The majority of patients (78%) used a nonopiate drug at least once during the trial. There were no significant correlations between concurrent drug use measures and opiate dependence treatment outcomes, indicating no simple linear relationship between these measures. However, when concurrent drug use was trichotomized into abstinent, intermittent, and heavy use groups, groups with intermittent use had superior outcome compared to both abstinent and heavy use groups in several contrasts. Conclusions: Intermittent use of non-opiate drugs is common during outpatient treatment for opiate dependence and may be a favorable prognostic indicator. This may support a "harm reduction" approach as opposed to a strict abstinence-oriented approach. Further research is needed to identify the optimal therapeutic stance toward other drug use during treatment for opiate dependence. (Author's abstract)
Affiliation :
New York State Psychiatric Inst., Substance Treatment Research Service, 600 West 168th Str., New York, NY 10032
Etats-Unis. United States.
Etats-Unis. United States.
Exemplaires
| Disponibilité |
|---|
| aucun exemplaire |