| Titre : | Heroin detoxification with buprenorphine on an inpatient psychiatric unit |
| Titre traduit : | (La buprénorphine dans la désintoxication à l'héroïne chez des patients hospitalisés dans une unité psychiatrique) |
| Auteurs : | DIPAULA B. A. ; R. SCHWARTZ ; I. D. MONTOYA ; D. BARRETT ; C. TANG |
| Type de document : | Périodique |
| Année de publication : | 2002 |
| Format : | 163-169 / tabl. |
| Note générale : |
Journal of Substance Abuse Treatment, 2002, 23, (3), 163-169 |
| Langues: | Anglais |
| Discipline : | TRA (Traitement et prise en charge / Treatment and care) |
| Mots-clés : |
Thésaurus mots-clés HEROINE ; BUPRENORPHINE ; COMORBIDITE ; HOPITAL PSYCHIATRIQUE ; EFFICACITEThésaurus géographique ETATS-UNIS |
| Résumé : |
ENGLISH : The purpose of this open-label, uncontrolled study was to evaluate the feasibility of administering off-label buprenorphine in combination with ancillary medications for inpatient short-term detoxification of heroin-dependent patients at a psychiatric facility. A sample of 20 heroin-dependent patients admitted to an urban psychiatric hospital was administered buprenorphine 6, 4, and 2 mg/day during the first, second, and third day of detoxification, respectively, and then observed during the fourth and fifth day. Eighty-five percent of the subjects abused other substances, 75% reported cocaine abuse/dependence, 75°,% had comorbid mood disorders. All subjects completed the medication phase of the study. No clinically significant adverse events were reported. There was a significant decrease in the Clinical Investigation Narcotic Assessment (CINA) total score between baseline and days 2 through 5. The results suggest that buprenorphine is well tolerated and may be beneficial for medically supervised short-term withdrawal from heroin for hospitalized psychiatric patients. (Editor's abstract.) |
| Note de contenu : | tabl. |
| Domaine : | Drogues illicites / Illicit drugs |
| Refs biblio. : | 21 |
| Affiliation : |
Walter P. Carter Ctr, Dept. Pharmacy Services, 630 W. Fayette st, Baltimore, MD 21201. E-mail : bdipaula@rx.umaryland.edu Etats-Unis. United States. |
| Numéro Toxibase : | 404015 |
| Centre Emetteur : | 04 CIRDD-51 |
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