| Titre : | Contribution of cannabis and MDMA ("ecstasy") to cognitive changes in long-term polydrug users (2004) |
| Titre traduit : | (Contribution du cannabis et de la MDMA dans les changements cognitifs observés chez les polytoxicomanes à long terme) |
| Auteurs : | R. I. DAFTER ; R. HOSHI ; A. C. TALBOT |
| Type de document : | Article : Périodique |
| Dans : | Psychopharmacology (Vol.173, n°3-4, May 2004) |
| Article en page(s) : | 405-410 |
| Langues: | Anglais |
| Discipline : | PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods) |
| Mots-clés : |
Thésaurus mots-clés MDMA-ECSTASY ; CANNABIS ; POLYCONSOMMATION ; DUREE ; USAGE REGULIER ; EVOLUTION ; COMPORTEMENT ; COGNITION |
| Résumé : | RATIONALE: Establishing whether cognitive changes follow long-term use of MDMA ("ecstasy") in humans has been difficult because of possible confounds with other drug use, particularly cannabis. Convincing evidence may be only obtained using experimental designs that account for such confounds. OBJECTIVE: In the present study, cognitive/behavioural measures were used to investigate whether long-term MDMA use or long-term cannabis use is responsible for the changes sometimes observed in recreational MDMA users. METHOD: Tests of attention and memory were administered to subjects who used both MDMA and cannabis, cannabis only, or neither drug. RESULTS: The main fording was that cannabis users, whether or not they also used MDMA, showed significantly impaired memory function on word free-recall and on immediate and delayed story recall compared to non-users. CONCLUSIONS: The findings high-light the importance of controlling for other drug use (particularly cannabis) when investigating persistent effects of MDMA in humans. (Author' s abstract) |
| Domaine : | Drogues illicites / Illicit drugs |
| Refs biblio. : | 35 |
| Affiliation : |
Psychology Dept, Glasgow Univ., 58 Hillhead Street, Glasgow, G12 8QB. Royaume-Uni. United Kingdom. |
| Numéro Toxibase : | 207782 |
| Centre Emetteur : | 02 Coordonnateur |
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