Titre : | Use of slow-release oral morphine for the treatment of opioid dependence |
Titre traduit : | (Utilisation de la morphine retard par voie orale dans le traitement de la dépendance aux opiacés) |
Auteurs : | D. KRAIGHER ; R. JAGSCH ; GOMBAS W. ; R. ORTNER ; H. EDER ; A. PRIMORAC ; G. FISCHER |
Type de document : | Périodique |
Année de publication : | 2005 |
Format : | 145-151 / fig. ; tabl. |
Note générale : | European Addiction Research, 2005, 11, (3), 145-151 |
Langues: | Anglais |
Discipline : | TRA (Traitement et prise en charge / Treatment and care) |
Mots-clés : |
Thésaurus mots-clés MORPHINE ; DISTRIBUTION CONTROLEE ; TRAITEMENT DE MAINTENANCE ; VOIE ORALE ; EFFICACITE ; OPIOIDESThésaurus géographique AUTRICHE |
Résumé : | Aims: In addition to methadone, other synthetic opioids are now available for the treatment of opioid dependence. The study investigated the treatment satisfaction of oral slow-release morphine for maintenance therapy in opioid-dependent patients in an open-label 3-week study. Design: We evaluated the treatment satisfaction of oral slow-release morphine hydrochloride for 3 weeks in 110 patients meeting the diagnosis of opioid dependence (DSM-IV 304.0) or polysubstance dependence (DSM-IV 304.9). Measurements: Primary outcome measures were the study retention rate, urinalysis for additional illicit consumption other than heroin, cravings and withdrawal symptoms 24 h after the last intake of the medication (duration of action of treatment). Findings: In total, 103 patients completed the study, representing a retention rate of 94%. Patients reported significant improvements in somatic complaints, as well as significant reductions in heroin and cocaine cravings (p |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 50 |
Affiliation : | Addiction Clinic, Department of General Psychiatry, University Hospital of Vienna, Vienna, Austria |
Numéro Toxibase : | 506214 |
Centre Emetteur : | 05 Marmottan |
Cote : | Abonnement |
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