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The relationship between non-injection drug use behaviors on progression to AIDS and death in a cohort of HIV seropositive women in the era of highly active antiretroviral therapy use
(Etude du lien entre un usage non injectable de drogues et la non évolution vers le Sida et la mort dans une cohorte de femmes séropositives au VIH dans le cadre d'un traitement antirétroviral.)
Auteur(s) :
KAPADIA, F. ;
COOK, J. A. ;
COHEN, M. H. ;
SOHLER, N. ;
KOVACS, A. ;
GREENBLATT, R. M. ;
CHOUDHARY, I. ;
VLAHOV, D.
Année :
2005
Page(s) :
990-1002
Langue(s) :
Anglais
Refs biblio. :
48
Domaine :
Drogues illicites / Illicit drugs
Discipline :
EPI (Epidémiologie / Epidemiology)
Thésaurus mots-clés
SEXE FEMININ
;
SIDA
;
MORT
;
FACTEUR DE RISQUE
;
INJECTION
;
ETUDE RETROSPECTIVE
Thésaurus géographique
ETATS-UNIS
Note générale :
Addiction, 2005, 100, (7), 990-1002, fig. ; tabl.
Résumé :
Aims: To evaluate the effects of longitudinal patterns and types of non-injection drug use (NIDU) on HIV progression in the highly active antiretroviral therapy (HAART) era. Design: Women's Interagency HIV Study (WIHS), a prospective cohort study conducted at six US sites. Methods: Data were collected semi-annually from 1994 to 2002 on 1046 HIV+ women. Multivariate Cox proportional hazards modeling was used to estimate relative hazards for developing AIDS and for death by pattern and type of NIDU. Findings: During follow-up, 285 AIDS events and 287 deaths, of which 177 were AIDS-related, were reported. At baseline, consistent and former NIDU was associated with CD4+ counts of 40 000 copies/ml (53% and 55%, respectively). Consistent NIDU reported less HAART use (53%) compared with other NIDU patterns. Stimulant use was associated with CD4+ cell counts of
Affiliation :
Center for Urban Epidemiologic Studies, New York Academy of Medicine, 1216 Fifth Avenue, room 556, New York NY 10029,
Etats-Unis. United States.
Etats-Unis. United States.