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Over 50 synthetic cathinone derivatives were detected via the EU Early Warning System (EU-EWS) between 2005 and 2013. This 'Perspective on drugs' explores new worrying localised and national outbreaks of injecting these substances and recommends[...]Article : Périodique
Le terme «stimulant» recouvre une large palette de substances légales et illégales. Parmi ces dernières, on trouve différentes familles de substances qui se ressemblent, mais qui ont aussi des différences s'agissant des effets et des conséquence[...]Rapport
La septième édition du Point SINTES décrit l'activité de veille, de collecte et d'analyse des produits en circulation par le dispositif au cours de l'année 2020. Malgré les perturbations liées à la crise sanitaire, 527 échantillons ont fait l'ob[...]Rapport
FRANÇAIS : Le Système d'identification national des toxiques et des substances (SINTES) est un dispositif piloté par l'OFDT depuis 1999 dans le but de décrire la composition des produits psychoactifs circulants en France. Il se fonde sur l'étud[...]Rapport
Comme chaque année, le dispositif SINTES coordonné par l'OFDT publie son bilan pour rendre compte des observations menées sur le territoire. En 2022, 623 collectes de produits psychoactifs ont été réalisées, soit une augmentation de 18 % par rap[...]Article : Périodique
A. DAVELUY ; M. LABADIE ; K. TITIER ; A. COURTOIS ; F. PENOUIL ; N. CASTAING ; F. HARAMBURU ; I. FAURE ; C. CAZANAVE ; J. M. DELILE ; V. LATOUR ; G. VALDENAIRE |Synthetic cathinones represent a large class of new popular drugs of abuse in France and in Europe, commonly called new psychoactive substances (NPS). We describe 11 cases of synthetic cathinone abuse reported to the Bordeaux Addictovigilance Ce[...]Article : Périodique
The results of a study performed on samples of ‘legal highs’ seized in head shops by law enforcement and health services in Poland between mid-2008 and mid-2011 are presented. In total, 449 preparations which differed in labelling, net masses, f[...]Article : Périodique
P. PAPA ; A. VALLI ; M. DI TUCCIO ; E. BUSCAGLIA ; E. BRAMBILLA ; G. SCARAVAGGI ; M. GALLO ; C. A. LOCATELLI |A number of new psychoactive substances (NPS) have been released in the last decade, and the list of NPS continues to grow. This paper reports a retrospective evaluation of the toxicological analyses in 1,445 suspected intoxication cases by psyc[...]Article : Périodique
The concept of a substance acting as a prodrug for an intended drug is not new and has been known and utilized with particular benefits within medicine for efficacy and patient safety. Prodrugs of psychoactive substances are also not particularl[...]Article : Périodique
Introduction. New synthetic drugs are appearing as old hallucinogen psychedelic drugs are reappearing. This article combines the findings from a variety of datasets to characterize the users in terms of gender, age, drug use patterns, and advers[...]Article : Périodique
S. DAVIES ; D. M. WOOD ; G. SMITH ; J. BUTTON ; J. RAMSEY ; R. ARCHER ; D. W. HOLT ; P. I. DARGAN |Background: The supply of recreational drugs has changed and users increasingly buy 'legal highs' over the Internet. Use of these is common and there is a potential for significant toxicity associated with their use. Aim: To determine the conte[...]Article : Périodique
This review summarizes the literature to date relating to pyrolysis and heated vapour ingestion of drugs of abuse. In this context, heating is referred to as smoking or pyrolysis, but these are generic descriptors that encompass numerous methods[...]Rapport
Le chemsex correspond à la consommation de substances psychoactives lors de rapports sexuels. Le but étant d'initier, faciliter, prolonger ou améliorer ces derniers à travers les différents effets psychoactifs des molécules consommées. Ces prati[...]Rapport
FRANÇAIS : Parmi les principaux points développés dans cette parution annuelle, l'agence de l'Union européenne insiste sur la hausse du nombre des décès par surdose sur le continent, la disponibilité élevée des nouvelles substances de synthèse [...]Rapport
FRANÇAIS : Parmi les principaux points développés dans cette parution annuelle, l'agence de l'Union européenne insiste sur la hausse du nombre des décès par surdose sur le continent, la disponibilité élevée des nouvelles substances de synthèse [...]Rapport
FRANÇAIS : L'Observatoire européen des drogues et des toxicomanies (EMCDDA) a rendu public le jeudi 6 juin son rapport européen sur les drogues 2019, lors d'une conférence de presse au siège de la Commission européenne à Bruxelles. Parmi les p[...]Rapport
FRANÇAIS : Le rebond rapide de l'offre et de la consommation de drogues à la suite des perturbations liées à la COVID-19 est l'un des problèmes mis en évidence dans le Rapport européen sur les drogues 2022. Ce rapport fournit la dernière vue d'[...]Rapport
Le 6 juillet 2017, des experts en toxicologie médico-judiciaire de laboratoires institutionnels et privés se sont réunis en vue d'établir des recommandations pour la réalisation d'investigations toxicologiques dans le cas de décès impliquant les[...]Article : Périodique
R. P. ARCHER ; R. TREBLE ; K. WILLIAMS |Historically, the appearance of new psychoactive materials (and hence the requirement for new reference standards) has been relatively slow. This position has now changed, with 101 new psychoactive substances reported to EMCDDA-Europol since 200[...]Article : Périodique
J. J. PALAMAR ; P. ACOSTA ; S. SHERMAN ; D. C. OMPAD ; C. M. CLELAND |Background: Novel psychoactive substances (NPSs) continue to emerge in the United States and worldwide. Few epidemiological studies have examined the prevalence and correlates of use. Objective: We examined the extent of NPS use in a high-risk [...]Article : Périodique
C. B. McNABB ; B. R. RUSSELL ; D. CAPRIOLI ; D. J. NUTT ; S. GIBBONS ; J. W. DALLEY |A recent and dramatic increase in the emergence of novel psychoactive substances ('legal highs') has left many governments unable to provide a timely response to an increasing number of potentially harmful drugs now available to the public. In r[...]Article : Périodique
FRANÇAIS : Le chemsex constitue à l'origine une pratique sexuelle accompagnée de produits pour exacerber le plaisir. Dans cet article, nous allons définir les pratiques de slam et de chemsex, et explorer les relations possibles avec une éventue[...]Rapport
ENGLISH: Spice (synthetic cannabinoids) and bath salts (synthetic cathinones) refer to two groups of designer drugs that have increased in popularity in recent years. These substances are created with analogs of commonly used illicit drugs. An [...]Article : Périodique
T. M. BRUNT ; E. LEFRANÇOIS ; T. GUNNAR ; A. ARPONEN ; T. SEYLER ; A. E. GOUDRIAAN ; A. McAULEY ; D. A. MCKEOWN ; V. DETREZ ; J. CSORBA ; D. DEIMEL ; V. AUWARTER ; J. KEMPF ; S. KAROLAK ; T. NÉFAU |Background and aims: Injecting drug use is a matter of public health concern, associated with risks of overdoses, addiction and increased risk of bloodborne viral transmissions. Self-reported data on substances injected can be inaccurate or subj[...]Article : Périodique
There is a growing concern about the availability of a new generation of "designer drug" stimulants that are marketed as "bath salts" and other household products. The products are not true bath salts and contain substituted cathinone stimulant [...]Article : Périodique
BACKGROUND: International media have been reporting about fatalities allegedly related to mephedrone, a popular recreational stimulant, but now a proportion of them have been confirmed. We aimed here at analyzing information relating to the circ[...]Article : Périodique
Purpose: Substance use disorder often coexists with other psychiatric disorders, resulting in the simultaneous use of recreational and prescription drugs. The authors aimed to identify potential pharmacokinetic and pharmacodynamic interactions b[...]Rapport
The term "bath salts" refers to an emerging family of drugs containing one or more synthetic chemicals related to cathinone, an amphetamine-like stimulant found naturally in the Khat plant. Reports of severe intoxication and dangerous health ef[...]Rapport
This situation report provides an assessment of the ability and abuse of synthetic Cathinones, commonly known as "bath salts," and "plant food." It also discusses production and distribution, lists common synthetic Cathinones, and provides backg[...]Article : Périodique
In 2000s, many synthetic cathinones have received a renewed popularity as designer drugs of abuse, particularly among young people. Despite being marketed as "bath salts" or "plant food" and labeled "not for human consumption", people utilize th[...]Article : Périodique
L. KARILA ; B. MEGARBANE ; O. COTTENCIN ; M. LEJOYEUX |New psychoactive substances (NPS) have completely modified the drug scene and the current landscape of addiction. Synthetic substances, such as substituted or synthetic cathinones, also known as "legal highs", are often produced and used to mimi[...]Article : Périodique
The term "synthetic drugs" is no longer a non-specific pharmacological phrase but one that describes a group of "designer drugs" which are responsible for global morbidity and mortality. In 2009, the United States (US) began experiencing the rap[...]Rapport
The objective of this review is to carry out a review of published and grey literature on the evidence of injecting and non-injecting stimulant use (particularly crack, cocaine and ATS) and their possible link to HIV, HCV & HBV vulnerability and[...]Article : Périodique
R. GRAY ; D. BRESSINGTON ; E. HUGHES ; A. IVANECKA |- What is known on the subject? Novel psychoactive substances (NPS) include synthetic drugs mimicking the effects of illicit drugs, e.g. synthetic cannabinoids, and herbs such as Salvia divinorum. NPS are substances that can trigger halluci[...]Rapport
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Comme l'année précédente, deux milieux ont été étudiés à savoir l'espace urbain, qui recouvre principalement la population en contact avec les structures de soin et d'accueil et l'espace festif (milieu techno), lequel cible des usages s'inscriva[...]Article : Périodique
K. MEYERS ; O. KAYNAK ; E. BRESANI ; B. CURTIS ; A. MCNAMARA ; K. BROWNFIELD ; K. C. KIRBY |Background: "Bath salts", a derivative of cathinone, a naturally occurring beta-ketone amphetamine analogue found in the leaves of the khat (Catha edulis) plant, is a potent class of designer drugs associated with significant medical and psychia[...]Rapport
UNODC launched the Global Synthetics Monitoring: Analyses, Reporting and Trends (SMART) Programme in September 2008. The Programme seeks to enhance the capacity of Member States and authorities in priority regions, to generate, manage, analyse a[...]Article : Périodique
F. SCHIFANO ; F. NAPOLETANO ; D. ARILLOTTA ; C. ZANGANI ; L. GILGAR ; A. GUIRGUIS ; J. M. CORKERY ; A. VENTO |Aims: Within the new psychoactive substances (NPS) scenario, several hundred different molecules, mostly including synthetic cannabinoids and cathinones, have been identified so far. The aims of the paper were to: (i) identify the number of synt[...]Article : Périodique
We have observed that data from national poison control centers (PCC) suggest that legislation banning specific legal highs correlates with a drastic reduction of PCC contacts. [Extract]Article : Périodique
ENGLISH: The substituted beta-keto amphetamine mephedrone (4-methylmethcathinone) was banned in the UK in April 2010 but continues to be used recreationally in the UK and elsewhere. Users have compared its psychoactive effects to those of 3,4-m[...]Article : Périodique
Article : Périodique
R. RINALDI ; G. BERSANI ; E. MARINELLI ; S. ZAAMI |The ever-growing number of novel psychoactive substances (NPS) that have been surfacing globally, as well as related changes in drug abuse trends, undoubtedly constitute a difficult and multifaceted challenge for psychiatry. The intake and abuse[...]Article : Périodique
The objective of the present study was to identify the metabolites of synthetic cathinone (SC), 3-chloromethcathinone (3-CMC), and to select a potential intake biomarker for this compound. The basis of the experiment was the analysis of blood an[...]Article : Périodique
Synthetic cathinones have recently emerged and grown to be popular drugs of abuse. Their dramatic increase has resulted in part from sensationalized media attention as well as widespread availability on the Internet. They are often considered "l[...]Article : Périodique
F. MEASHAM ; K. MOORE ; R. NEWCOMBE ; Z. WELCH |Significant changes in British recreational drug use were seen throughout 2009, with the emergence and rapid growth in the availability and use of substituted cathinones or 'M-Cats' (most notably mephedrone and methylone), a group of psychoactiv[...]