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Documents disponibles dans cette catégorie (139)
Article : Périodique
The illicit marketplace of substances of abuse continually offers for sale legal alternatives to controlled drugs to a large public. In recent years, a new group of designer drugs, the synthetic cathinones, has emerged as a new trend, particular[...]Rapport
This publication presents the data and findings of the risk assessment on 1-(3-chlorophenyl)-2-(methylamino)propan-1-one (3-chloromethcathinone, 3-CMC), carried out by the extended Scientific Committee of the EMCDDA on 19 November 2021. On the b[...]Rapport
This publication presents the data and findings of the risk assessment on 2-(methylamino)-1-(3-methylphenyl)propan-1-one (3-methylmethcathinone, 3-MMC), carried out by the extended Scientific Committee of the EMCDDA on 18 November 2021. On the b[...]Article : Périodique
Following the initial popularity of mephedrone (4-methylmethcathinone) there has been a stream of new "recreational drugs" entering the global market. The lack of clinical studies on the effects and toxicity of these drugs has made interpretatio[...]Article : Périodique
A. TURCANT ; M. DEGUIGNE ; S. FÉREC ; C. BRUNEAU ; I. LEBORGNE ; B. LELIÈVRE ; C. GEGU ; F. JEGOU ; C. ABBARA ; G. LE ROUX ; D. BOELS |For the last 10 years, recreational use of new psychoactive substances (NPS) with hallucinogenic properties was more and more described either in a context of consumption during a rave-party or at home alone or in small group. A review of 62 cas[...]Article : Périodique
In recent years, the recreational use of new psychoactive substances (NPS) has increased all around the world. They are designed to cause similar effects to controlled drugs and are considered as alternative to illegal drugs. Among NPS, derivati[...]Article : Périodique
A. TURCANT ; D. BOELS ; A. G. HELFER ; S. FÉREC ; M. BRETAUDEAU DEGUIGNE ; B. LELIÈVRE ; M. R. MEYER ; H. H. MAURER |Objective: 4-Methyl-N-ethylcathinone (4-MEC) is a novel designer drug of the beta-keto amphetamine family. A case of a mixed poisoning by 4-MEC and gamma-butyrolactone (GBL) is described. Two and half hours after an injected 0.25-0.5 g 4-MEC dos[...]Article : Périodique
A. PETIT ; F. LEVY ; M. REYNAUD ; M. LEJOYEUX ; L. KARILA ; R. ZARMDINI ; W. LOWENSTEIN |L'essentiel : • Il n'existe pas de traitement de substitution à la cocaïne, à la méthamphétamine et aux amphétamines. • Aucun agent pharmacologique n'a d'AMM dans le traitement des symptômes et des complications liés à l'usage de ces drogues. [...]Rapport
This report presents new findings from the ESCAPE (European Syringe Collection and Analysis Project Enterprise) network, based on the chemical analysis of the contents of used syringes across sentinel sites in Europe. Syringes were collected in [...]Article : Périodique
A synthetic cathinone called 4-methylethcathinone (4-MEC) emerged online in 2010, and was cyber-marketed to be a replacement for mephedrone. The study aimed to present user experiences of 4-MEC as reported on the Internet, with a focus on user p[...]Article : Périodique
An overview of recent developments in the analytical detection of new psychoactive substances (NPSs)
New psychoactive substances (NPSs), sometimes referred to as "legal highs" in more colloquial environments/the media, are a class of compounds that have been recently made available for abuse (not necessarily recently discovered) which provide s[...]Article : Périodique
S. NORDMANN ; T. NÉFAU ; J. MICALLEF ; C. DUPLESSY ; J. C. CATUSSE ; E. FRAUGER |FRANÇAIS : Objectif : L'objectif de cette étude est de décrire les substances psychoactives retrouvées dans les seringues usagées. Méthodes : Les seringues ont été collectées sur Marseille en mars 2014 dans 9 points de collecte (automates, rue[...]Article : Périodique
G. GATICA-BAHAMONDE ; E. A. GODYNYUK ; J. NEICUN ; E. ROBERTS ; M. M. TANGERLI ; R. VAN KESSEL ; K. CZABANOWSKA ; K. HUMPHREYS ; A. ROMAN-URRESTARAZU |Background and Aims: New psychoactive substances (NPS) pose challenges not only due to their harms to users but also because they are difficult to monitor with traditional epidemiologic methods. Wastewater-based epidemiology (WBE) offers a relia[...]Article : Périodique
W. ZUKIEWICZ-SOBCZAK ; J. ZWOLINSKI ; J. CHMIELEWSKA-BADORA ; E. KRASOWSKA ; J. PIATEK ; P. SOBCZAK ; A. WOJTYLA ; E. FORNAL ; A. KUCZUMOW ; P. BILINSKI |"Legal highs" known also as "smarts", "legal drugs" or "boosters" contain in their composition psychoactive substances the production, sale and possession of which are not prohibited in legislation. They are offered for sale under the cover of c[...]Article : Périodique
Analytical profiles of "legal highs" containing cathinones available in the area of Lisbon, Portugal
V. M. R. ZANCAJO ; J. BRITO ; M. P. CARRASCO ; M. R. BRONZE ; R. MOREIRA ; A. LOPES |Thirteen "legal highs" were purchased in different "smart shops" in the area of Lisbon, Portugal, during the month of February 2013. The samples were analyzed by a battery of analytical methods including Fourier transform infra-red (FTIR), gas c[...]Article : Périodique
The steady increase of new drugs of abuse on the illicit drug market is a great challenge for analytical toxicologists. Because most of these new drugs or drug classes are not included in established analytical methods targeting classic drugs of[...]Article : Périodique
C. WEBER ; J. L. SMITH ; J. SODERSTROM ; S. BURROWS ; D. MCCUTCHEON ; F. OOSTHUIZEN ; D. M. FATOVICH |Introduction: The burden of acute illicit drug use in Australia is largely unknown. Establishing a prospective drug surveillance system in emergency departments using analytical confirmation may facilitate the early identification of emerging dr[...]Rapport
FEWS collected samples from the internet, headshops, music festivals, the police and health clinics to identify NPS which are present in the UK or being offered for sale in the UK market. One of the aims of the collection plans is to collect inf[...]Article : Périodique
New psychoactive substances (NPS) are present on the Italian illicit markets, but data from the analysis of biological samples to evaluate their real consumption are rare. For this reason, an epidemiological study was carried out by means of a u[...]Texte legislatif
EXTRAIT Article 1er. - Sont interdits la production, la mise sur le marché et l'emploi des substances suivantes : Acétorphine ; Acétylalphaméthylfentanyl ; Alphacétylméthadol ; Alphaméthylfentanyl ; Bêta-hydroxyfentanyl ; Bêta-hydroxy-mét[...]Texte legislatif
EXTRAIT Art. 2. - L'annexe III de l'arrêté du 22 février 1990 susvisé est modifiée comme suit : Cette annexe comprend : - les substances ci-après désignées ; - leurs stéréo-isomères, dans tous les cas où ils peuvent exister conformément à la[...]Texte legislatif
EXTRAIT Considérant que la cathinone possède une structure chimique analogue à celle de l'amphétamine, inscrite sur la liste des substances classées comme stupéfiantes, et se trouve être le chef de file de la famille des cathinones qui possèden[...]Texte legislatif
EXTRAITS : Article 1. - A l'annexe I de l'arrêté du 22 février 1990 susvisé fixant la liste des substances classées comme stupéfiants, sont ajoutés les mots : U-47700 ou 3,4-dichloro-N-[2-(dimethylamino) cyclohexyl]-N-methylbenzamide et Buty[...]Texte legislatif
EXTRAIT Article 1. - A l'annexe I de l'arrêté du 22 février 1990 susvisé fixant la liste des substances classées comme stupéfiants, sont ajoutés les mots : acétylfentanyl et MT-45 ou 1-cyclohexyl-4-(1,2-diphényléthyl) pipérazine. Article 2. [...]Texte legislatif
EXTRAIT Art. 1er. - Sont inscrits à la section II des tableaux des substances vénéneuses les produits suivants : [...]Article : Périodique
A. AMELINE ; A. BLANCHOT ; N. ARBOUCHE ; J. S. RAUL ; P. KINTZ |FRANÇAIS : Le chemsex, contraction des termes anglais « chemical » et « sex », provient de la culture gay anglo-saxonne et désigne le fait de consommer des produits psychotropes pendant des activités sexuelles pour les rendre plus intenses, plu[...]Article : Périodique
A. LEVASSEUR ; A. KNAPP-GISCLON ; C. MAYER-DUVERNEUIL ; I. ETTING ; G. LORIN DE LA GRANDMAISON ; J. C. ALVAREZ |Background: "New psychoactive substances" (NPS), has been described as a "growing global epidemic". The aim of our study was to document acute and chronic lesions that can be induced by NPS from autopsy cases for which complete toxicological ana[...]Article : Périodique
The emergence of 'bath salts' products containing synthetic cathinones represents a global public health threat. Synthetic cathinones have significant abuse potential, and the effects of high-dose administration can be life-threatening. More pre[...]Article : Périodique
Background: Recreational use of designer substances containing synthetic cathinones such as mephedrone, commonly sold as "bath salts," has recently been increasing in the United States (National Institute on Drug Abuse. Available at: http://www.[...]Article : Périodique
Use of synthetic cathinones ("bath salts") has been associated with tens of thousands of emergency department visits. Few surveys, however, query use. Research on "bath salt" use is needed, especially in high-risk populations, to inform preventi[...]Article : Périodique
Synthetic cathinones are an emerging class of designer drugs abused for psychostimulant and hallucinogenic effects similar to cocaine, methylenedioxymethamphetamine (MDMA), or other amphetamines. Abuse of synthetic cathinones, frequently include[...]Chapitre
R. A. GLENNON | 2014The term "synthetic cathinones" is fairly new, but, although the abuse of synthetic cathinones is a recent problem, research on cathinone analogs dates back > 100 years. One structural element cathinone analogs have in common is an alpha-aminoph[...]Article : Périodique
"Bath salts" is one street name for a family of synthetic cathinones that display pharmacological effects resembling cocaine and commonly abused amphetamines. Despite extensive legislation aimed at the criminalization of bath salts, several desi[...]Rapport
J. CSORBA ; T. FIGECZKI ; J. KISS ; K. MEDGYESI-FRANK ; A. PÉTERFI | Budapest : Magyar Ökumenikus Segélyszervezet | 2016Hungarian Interchurch Aid's project "Breaking the Drug Cycle" was brought to life by the need to provide reliable information on substances used by PWIDs, including temporal and geographical patterns by the help of a comprehensive survey. Gener[...]Article : Périodique
Cathinone is a potent CNS stimulant found in khat leaves. Cathinone and synthetic cathinone-derivatives have become popular recreational drugs in recent years, commonly marketed as "legal highs." In addition to acute physical and psychiatric adv[...]Article : Périodique
Synthetic cathinones are designer drugs of the phenethylamine class, structurally and pharmacologically similar to amphetamine, 3,4-methylenedioxymethamphetamine (MDMA), cathinone and other related substances. New analogues, legal at least, unti[...]Article : Périodique
C. SASTRE ; C. MAZOYER ; C. MAYER ; J. GROSJEAN ; V. DI FAZIO ; E. SAUSSEREAU |FRANÇAIS : L'apparition de nouvelles substances psychoactives s'explique bien évidemment par les supposées similarités fonctionnelles des substances qu'elles « copient » tout en représentant, dans certains cas, une alternative légale à d'autres[...]Article : Périodique
N. BRAHIM ; L. KARILA ; C. LUCET ; A. BENYAMINA |FRANÇAIS : La relation entre le sexe et les drogues est établie depuis longtemps. Toutefois, l'apparition récente des nouveaux produits de synthèse, et notamment les cathinones de synthèse, a fait émerger des nouveaux modes de consommations ass[...]Article : Périodique
A. PÉTERFI ; A. TARJAN ; G. HORVATH ; T. CSESZTREGI ; A. NYIRADY |The spread of synthetic cathinone injecting is a new phenomenon observed in recent years in Hungary. Until 2010, when the first anecdotal reports on cathinone injecting appeared, injecting was associated with the use of heroin and amphetamine. I[...]Article : Périodique
Background: The study presents the characteristics of the use of new psychoactive substances (NPS), the perceived problems experienced by users, and the reasons for cessation or cutting down. The research focused mainly on synthetic cathinones a[...]Article : Périodique
T. CASTAING-CORDIER ; A. BENAVIDES RESTREPO ; D. DUBOIS ; V. LADROUE ; F. BESACIER ; A. BULETE ; C. CHARVOZ ; A. GOUPILLE ; D. JACQUEMIN ; P. GIRAUDEAU ; J. FARJON |New psychoactive substances (NPS) have become a serious threat for public health due to their ability to be sold in the street or on internet. NPS are either derived from commercial drugs which are misused (recreational rather than medical use) [...]Article : Périodique
FRANÇAIS : Le terme « chemsex » désigne des relations sexuelles pratiquées sous l'influence de divers types de drogues illicites, en particulier des nouveaux produits de synthèse (NPS), mais également des médicaments consommés avant ou pendant [...]Brochure
RESPADD | 2016Ce livret vous donnera les principales informations sur le chemsex, des conseils sur la manière dont vous pouvez intervenir simplement et des indications sur les ressources et formations disponibles pour aller plus loin.Article : Périodique
L'ESSENTIEL : - Le chemsex est une pratique minoritaire parmi les hommes homosexuels, mais très fréquente chez ceux consultant pour IST. - C'est une conduite à haut risque infectieux, addictologique et psychiatrique. - La prise en charge est [...]Article : Périodique
M. MARILLIER ; A. BATISSE ; C. RICHEVAL ; V. LABROUVE ; M. MARTINEZ ; D. ALLORGE ; M. GREGOIRE ; P. BATEL ; T. NÉFAU ; C. CHEVALLIER ; J. M. GAULIER ; S. DJEZZAR |"Chemsex" means sex, generally between men, occurring under the influence of drugs taken immediately before and/or during the sexual session. "Slam" is defined by injection of psychostimulant drugs in the same context. The Parisian Addictovigila[...]