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Article : Périodique
North America is currently experiencing an opioid crisis. One proposed solution to combat problems associated with injection drug use is the use of supervised injection facilities. These facilities provide drug users a space to inject pre-obtain[...]Congrès
M. CASTAGNÉ | 1987FRANÇAIS : L'auteur voit un pharmacien dealer de Neocodion pour une ancienne cliente, puis ensuite cherche son aide; l'auteur procède à une réflexion sur ce type de transaction, culpabilisante pour tous les acteurs; le produit agit plus comme u[...]Périodique
VASWANI M. ; N. G. DESAI | 2004ENGLISH : Various risk behaviors promote the spread of HIV in drug addicts. Reflecting the substantial regional and geographic differences in the impact of HIV, its prevalence rates vary from country to country. In view of increasing reports o[...]Article : Périodique
FRANÇAIS : Dans le cadre de deux importantes études menées sur le comportement à risque lié au VIH parmi des usagers d'opioïdes et d'amphétamines dans le Nord-Ouest de l'Angleterre, on a comparé le comportement sexuel et le partage de matériel[...]Article : Périodique
Background and aims: The full burden of the opioid epidemic on US hospitals has not been described. We aimed to estimate how heroin (HOD) and prescription opioid (POD) overdose-associated admissions, costs, outcomes and patient characteristics h[...]Article : Périodique
J. NEALE ; C. BROWN ; A. N. C. CAMPBELL ; J. D. JONES ; V. E. METZ ; J. STRANG ; S. D. COMER |BACKGROUND AND AIMS: Providing take-home naloxone (THN) to people who use opioids is an increasingly common strategy for reversing opioid overdose. However, implementation is hindered by doubts regarding the ability of people who use opioids to [...]Article : Périodique
M. GUILLOU-LANDREAT ; A. DANY ; G. CHALLET-BOUJU ; E. J. LAFORGUE ; J. CHOLET ; J. LEBOUCHER ; J. B. HARDOUIN ; C. VICTORRI-VIGNEAU ; M. GRALL-BRONNEC |BACKGROUND: The resurgence of heroin use and the misuse of pharmaceutical opioids are some of the reasons for a worldwide increase in opioid dependence. Opioid Medication Therapies (OMT) have amply demonstrated their efficacy. From a medical poi[...]Article : Périodique
E. HOCH ; D. NIEMANN ; R. VON KELLER ; M. SCHNEIDER ; C. M. FRIEMEL ; U. W. PREUSS ; A. HASAN ; O. POGARELL |We conducted a review of systematic reviews (SRs) and randomized-controlled trials (RCTs) to analyze efficacy and safety of cannabis-based medication in patients with mental disorders. Five data bases were systematically searched (2006-August 20[...]Rapport
Europol | 2017Drug markets remain the largest criminal markets in the EU. More than one third of the criminal groups active in the EU are involved in the production, trafficking or distribution of various types of drugs. The trade in illicit drugs generates m[...]Article : Périodique
Background: The illegal drug trade is often, and plausibly, asserted to be the largest illegal market, globally and in many individual countries. It is also claimed that a large share of its revenues is laundered, though there are no estimates o[...]Rapport
M. BALL ; R. BROADHURST ; H. TRIVEDI | Canberra : Australian Institute of Criminology | Statistical Bulletin, ISSN 2206-7302 | 2019This bulletin provides a snapshot of the sale and distribution of fentanyl and its analogues across several popular illicit darknet markets. Data collected daily from six darknet markets between 2 January and 23 February 2019 reveal the amount, [...]Article : Périodique
Fentanyls as a class of drug have pharmacological properties that make them more likely to lead to overdose than other opioids. In addition to high potency and rapid onset of respiratory depression, these drugs also induce respiratory muscle sti[...]Article : Périodique
In April 2023, the Taliban banned poppy cultivation and the trade of all narcotics. This caused a 95% reduction in opium production. Usually, that would be good news. But there is a substantial worry: synthetic opioids might fill the void left b[...]Périodique
G. E. BIGELOW | 1991FRANÇAIS : La méthode générale consiste à comparer le profil d'activité d'une drogue-test aux profils d'un placebo et d'une drogue connue comme étant addictive. Les drogues dont le profil d'activité est similaire à celui de drogues connues comm[...]Article : Périodique
A. L. SIBLEY ; R. BAKER ; X. A. LEVANDER ; A. RAINS ; S. M. WALTERS ; K. NOLTE ; D. C. COLSTON ; H. M. PISCALKO ; C. A. SCHALKOFF ; E. BIANCHET ; S. CHEN ; P. DOWD ; M. JAEB ; P. D. FRIEDMANN ; R. J. FREDERICKSEN ; D. W. SEAL ; V. F. GO |Background: Substance use stigma is a form of group-based exclusion, and delineating pathways from stigma to poor health requires a deeper understanding of the social dynamics of people who use drugs (PWUD). Outside of recovery, scant research h[...]Article : Périodique
Background: The past decade has seen over a four-fold increase in deaths from opioid overdose in the United States. To address this growing epidemic, many localities initiated policies to expand access to naloxone (a drug that reverses the effec[...]NouveautéArticle : Périodique
V. CATALANI ; D. ARILLOTTA ; J. M. CORKERY ; A. GUIRGUIS ; A. VENTO ; F. SCHIFANO |COVID-19-related disruptions of people and goods' circulation can affect drug markets, especially for new psychoactive substances (NPSs). Drug shortages could cause a change in available NPS, with the introduction of new, unknown, substances. Th[...]Article : Périodique
Purpose: To examine the prevalence and correlates of college student use of illicit substances including cocaine, designer drugs, and nonmedical use of prescription stimulants and opioids, and to identify how different drug-related perceptions a[...]Article : Périodique
E. ZUCCATO ; S. CASTIGLIONI ; R. BAGNATI ; C. CHIABRANDO ; P. GRASSI ; R. FANELLI |It is now well established that residues from therapeutic drugs consumed by humans can end up, through the sewage system, in the surface water of populated areas. Given that the global production of major illicit drugs is comparable to that of w[...]Article : Périodique
Background: Illicitly manufactured fentanyl and its analogues are appearing in countries throughout the world, often disguised as heroin or counterfeit prescription pills, with resulting high overdose mortality. Possible explanations for this ph[...]Périodique
S. E. McCABE ; C. J. BOYD ; TETER C. J. | 2005The illicit use of opioid analgesics represents a growing problem among American adolescents. In order to examine the. correlates associated with the illicit use of opioid analgesics, a nationally representative sample of 4,522 high school senio[...]Article : Périodique
For nearly a century heroin has dominated the illegal opioid trade. The global supply of heroin is estimated to generate tens of billions of dollars in revenues a year and its illegal use has long been the source of many societal harms. The arri[...]Périodique
M. J. KREEK | 1990FRANÇAIS : L'action des opiacés dans la dépression de l'activité des cellules NK n'est pas directe ni chimiquement significative. L'effet observé aurait pour origine indirecte une atteinte neuroendocrine d'ailleurs normalisée lors d'un traiteme[...]Chapitre
EISENSTEIN T.K. ; HILBURGER M.E. ; D. M. P. LAWRENCE | 1995Dans ce chapitre, les auteurs étudient les effets de la morphine et des autres opioïdes sur les cellules du système immunitaire et envisagent différentes hypothèses concernant les mécanismes immunodépressifs. Ces substances ont une action direct[...]Périodique
H. U. BRYANT ; E.W. BERNTON ; HOLADAY J.W. | 1990FRANÇAIS : L'action des opiacés sur la fonction immunitaire peut être directe (récepteurs des lymphocytes) ou indirecte (récepteurs du système nerveux central). Elle pourra s'exprimer par une augmentation de la production de corticoïdes endogèn[...]Article : Périodique
FRANÇAIS : Introduction : Une consommation chronique d'opiacés est responsable de déficits neurocognitifs, comme démontrés dans de nombreuses études. Néanmoins, l'impact neurocognitif du traitement à la méthadone (opioïde de synthèse) n'a pas r[...]Article : Périodique
V. VINDENES ; D. JORDBRU ; A. B. KNAPSKOG ; E. KVAN ; G. MATHISRUD ; L. SLORDAL ; J. MORLAND |Aims: When non-alcohol drugs are detected in blood samples from apprehended drivers in Norway, individualised expert opinions are required to evaluate degree of impairment. For alcohol, legislative limits have been in use since 1936. To harmoniz[...]Article : Périodique
E. CHILDS ; K. B. BIELLO ; P. K. VALENTE ; P. SALHANEY ; D. L. BIANCARELLI ; J. OLSON ; J. J. EARLYWINE ; B. D. L. MARSHALL ; A. R. BAZZI |Background: Harm reduction services, which typically provide overdose education and prevention with distribution of naloxone and other supplies related to safer drug use, help reduce opioid-related overdose and infectious disease transmission. H[...]Article : Périodique
L. ARCHAMBAULT ; M. GOYER ; J. SABETTI ; M. PERREAULT |Background: Engagement of health care professionals represents an important factor for successful implementation of new practices. To support these professionals' involvement, it is essential to understand their perspective. This study describes[...]Périodique
BOYARSKY B. K. ; E. F. McCANCE-KATZ | 2000FRANÇAIS : Revue des traitements pharmacologiques standards et nouveaux pour traiter la dépendance à l'alcool, aux opioïdes, à la cocaïne et à la nicotine. Des directives pour traiter un patient présentant plusieurs dépendances sont indiquées a[...]Article : Périodique
S. G. MITCHELL ; S. M. KELLY ; B. S. BROWN ; H. S. REISINGER ; J. A. PETERSON ; RUHF A. ; M. H. AGAR ; R. P. SCHWARTZ |Both heroin-addicted individuals and methadone maintenance patients are likely to face untreated opioid withdrawal while incarcerated. Limited research exists concerning the withdrawal experiences of addicted inmates and their impact on individu[...]Article : Périodique
C. CHENAF ; J. L. KABORE ; J. DELORME ; B. PEREIRA ; A. MULLIEZ ; L. ROCHE ; A. ESCHALIER ; N. DELAGE ; N. AUTHIER |PURPOSE: Opioid analgesic use in chronic non-cancer pain (CNCP) is increasingly prevalent, but the benefits and risks are inadequately understood. In France, tramadol is one of the most used prescription opioids, but studies on its misuse liabil[...]Article : Périodique
A. ROUSSIN ; T. SOEIRO ; C. FOUQUE ; E. JOUANJUS ; E. FRAUGER ; N. FOUILHE ; M. MALLARET ; J. MICALLEF ; M. LAPEYRE-MESTRE ; French Addictovigilance Network |AIM: To assess recent developments in non-medical tramadol use, tramadol use disorder, illegal procurement, and deaths. METHODS: Repeated cross-sectional analysis of data collected nationwide from 2013-2018. Analysis through the multisource mon[...]Article : Périodique
Introduction: Given the relatively recent growth in access to heroin and a more permissive atmosphere surrounding its use, we hypothesized that an increasing number of persons with limited experience and tolerance to opioids would experiment wit[...]Article : Périodique
The United States is experiencing an epidemic of drug overdose (poisoning) deaths. Since 2000, the rate of deaths from drug overdoses has increased 137%, including a 200% increase in the rate of overdose deaths involving opioids (opioid pain rel[...]Article : Périodique
B. NOSYK ; B. D. L. MARSHALL ; B. FISCHER ; J. S. G. MONTANER ; E. WOOD ; T. KERR |Background: The nonmedical use of prescribed opioids (POs) has increased across North America over the past decade. Our objective was to identify changes in the availability of POs and other illicit drugs among drug users in a Canadian setting. [...]Périodique
F. ANDERSON ; S. RICE ; OPERE C. ; K. AL-ZADJALI ; OHIA S.E. | 1996FRANÇAIS : Les auteurs ont étudié l'effet des opioïdes et des peptides apparentés, sur la neurotransmission sympathique au niveau de l'iris de bovins, et ont évalué l'usage de l'iris de bovin comme modèle possible pour les études pharmacologiqu[...]Article : Périodique
S. E. LANKENAU ; M. TETI ; K. SILVA ; J. JACKSON BLOOM ; A. HAROCOPOS ; M. TREESE |BACKGROUND: Prescription opioids are the most frequently misused class of prescription drugs amongst young adults. Initiation into prescription opioid misuse is an important public health concern since opioids are increasingly associated with dr[...]Article : Périodique
BACKGROUND Opioid dependence is associated with low rates of treatment-seeking, poor adherence to treatment, frequent relapse, and major societal consequences. We aimed to assess the efficacy, safety, and patient-reported outcomes of an injectab[...]Article : Périodique
Cette communication revient sur le succès du tramadol, un antidouleur innovant qui s'est imposé comme le premier antalgique accessible sur ordonnance prescrit par les médecins généralistes français à partir du milieu des années 2000. Elle vise d[...]Article : Périodique
Do drug dealers entice nonusers with free samples? Police, the popular press, and social media users say so, but crime researchers have found little support for this theory and argue instead that sample distribution is an unsound strategy for il[...]Article : Périodique
B. MEGARBANE ; GUEYE P. ; F. BAUD |FRANÇAIS : Les circonstances de consommation simultanée de benzodiazépines et de produits opiacés ou opioïdes sont nombreuses, comme en anesthésiologie, pour le traitement de la douleur aiguë ou chronique ou dans Ie cadre des traitements de sub[...]Article : Périodique
Périodique
P. BEAULIEU | 2000FRANÇAIS : Ces deux systèmes, opioïde et cannabinoïde, ont de nombreux points communs tels l'existence de ligands endogènes et de récepteurs couplés à des protéines G. Il existe une interconnexion entre les récepteurs opioïdes et cannabinoïdes [...]Article : Périodique
Les médicaments opioïdes prescrits à long terme dans le cadre des troubles liés à l'usage d'opioïdes (Traitements agonistes opioïdes, TAOs) représentent une singularité dans le traitement des conduites addictives. En sus des procédures ordinaire[...]Article : Périodique
E. FRAUGER ; F. KHELOUFI ; Q. BOUCHERIE ; E. MONZON ; L. JUPIN ; N. RICHARD ; M. MALLARET ; J. MICALLEF |FRANÇAIS : Ces dernières décennies, on a observé un changement du panorama des opioïdes consommés avec la commercialisation des médicaments de substitution aux opiacés, une augmentation de la consommation d'analgésiques opioïdes et récemment l'[...]Rapport
Bureau for International Narcotics and Law Enforcement Affairs | Washington, DC : U.S. Department of State | 2022The Department of State's International Narcotics Control Strategy Report (INCSR) - due to Congress March 1st annually - is prepared in accordance with §489 of the Foreign Assistance Act of 1961, as amended (the "FAA," 22 U.S.C. §2291). The INCS[...]Rapport
Bureau for International Narcotics and Law Enforcement Affairs | Washington, DC : U.S. Department of State | 2023While the public health crisis of COVID-19 and its concomitant effects on drug trafficking, control, and use abated in 2022, the crisis of substance use continued, though it did not intensify to the same degree as in the past two years. Provisio[...]Article : Périodique
N. BOUMPARIS ; E. KARYOTAKI ; M. P. SCHAUB ; P. CUIJPERS ; H. RIPER |Commentary: It works, but only if they use it - addressing treatment adherence and attrition in internet interventions for illicit substance use. Stockings E.A., p. 1533-1534. Background and Aims: Research has shown that internet intervention[...]Article : Périodique
This paper reports on changes in substance use and substance dependence symptoms - without intervention - among young adult multidrug users in the club scene, ages 18-29, (N = 444) who participated in a natural history study. Computer-assisted p[...]