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Associations between marijuana use and cardiovascular risk factors and outcomes: A systematic review / N. V. RAVI ; M. GHASEMIESFE ; D. KORENSTEIN ; T. CASCINO ; S. KEYHANI in Annals of Internal Medicine, Vol.168, n°3 (6 February 2018)
Titre : Associations between marijuana use and cardiovascular risk factors and outcomes: A systematic review Type de document : Périodique Auteurs : N. V. RAVI ; M. GHASEMIESFE ; D. KORENSTEIN ; T. CASCINO ; S. KEYHANI Année de publication : 2018 Article en page(s) : 187-194 Langues : Anglais (eng) Mots-clés : Thésaurus TOXIBASE
CANNABIS ; APPAREIL CARDIOVASCULAIRE ; FACTEUR DE RISQUE ; ARRET CARDIAQUE ; INFARCTUS ; OBESITE ; MORTALITE
Mots-clés : evidence-based Discipline : PAT Pathologie organique / Organic pathology Résumé : ENGLISH:
Background: Marijuana use is increasing in the United States, and its effect on cardiovascular health is unknown.
Purpose: To review harms and benefits of marijuana use in relation to cardiovascular risk factors and clinical outcomes.
Data Sources: PubMed, MEDLINE, EMBASE, PsycINFO, and the Cochrane Library between 1 January 1975 and 30 September 2017.
Study Selection: Observational studies that were published in English, enrolled adults using any form of marijuana, and reported on vascular risk factors (hyperglycemia, diabetes, dyslipidemia, and obesity) or on outcomes (stroke, myocardial infarction, cardiovascular mortality, and all-cause mortality in cardiovascular cohorts).
Data Extraction: Study characteristics and quality were assessed by 4 reviewers independently; strength of evidence for each outcome was graded by consensus.
Data Synthesis: 13 and 11 studies examined associations between marijuana use and cardiovascular risk factors and clinical outcomes, respectively. Although 6 studies suggested a metabolic benefit from marijuana use, they were based on cross-sectional designs and were not supported by prospective studies. Evidence examining the effect of marijuana on diabetes, dyslipidemia, acute myocardial infarction, stroke, or cardiovascular and all-cause mortality was insufficient. Although the current literature includes several long-term prospective studies, they are limited by recall bias, inadequate exposure assessment, minimal marijuana exposure, and a predominance of low-risk cohorts.
Limitation: Poor- or moderate-quality data, inadequate assessment of marijuana exposure and minimal exposure in the populations studied, and variation in study design.
Conclusion: Evidence examining the effect of marijuana on cardiovascular risk factors and outcomes, including stroke and myocardial infarction, is insufficient.
Primary Funding Source: National Heart, Lung, and Blood Institute. (PROSPERO: CRD42016051297).
Les auteurs de cette revue des études examinant les effets de l'usage du cannabis sur le coeur et la circulation ont conclu que «les preuves examinant l'effet de la marijuana sur les facteurs de risque cardiovasculaire et les résultats y compris l'accident vasculaire cérébral et l'infarctus du myocarde sont insuffisantes». [IACM, 11/02/2018]
Domaine : Drogues illicites / Illicit drugs Sous-type de document : Revue de la littérature / Literature review Refs biblio. : 52 Affiliation : The Wright Center for Graduate Medical Education, Scranton, Pennsylvania, USA Permalink :
in Annals of Internal Medicine > Vol.168, n°3 (6 February 2018) . - 187-194[article]Cocaine and the heart / R. A. KLONER in New England Journal of Medicine, Vol.348, n°6 (February 6, 2003)
Titre : Cocaine and the heart Titre traduit : (Cocaïne et coeur) Type de document : Périodique Auteurs : R. A. KLONER ; S. H. REZKALLA Année de publication : 2003 Article en page(s) : 487-488 Présentation : fig. Langues : Anglais (eng) Mots-clés : Thésaurus TOXIBASE
COCAINE ; EFFET SECONDAIRE ; ARRET CARDIAQUE ; INFARCTUS ; APPAREIL CARDIOVASCULAIRE ; COEUR
Discipline : PRO Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods Résumé : The litterature is replete with cases of acute myocardial infarction after cocaine use, which probably involves several mechanisms as seen in a very accurate picture. The risk of acute myocardial infarction is highest within the first hour after cocaine use and then rapidly declines. However, some reports suggest that myocardial infarction can occur as early as minutes after cocaine administration or as late as few days afterward. There is no clear relation between the dose of cocaine and the occurrence of an acute coronary event. Myocardial infarction may develop in first-time users, occasional users and long-term users. This article describes this disease and shows the best way to care this ailment in the emergency department. (Extract of the publication) Domaine : Drogues illicites / Illicit drugs Affiliation : Division of Cardiovascular Medicine, Keck School of Medicine, Univ. of Southern California, Los Angeles, USA Numéro Toxibase : 1300507 Centre Emetteur : 13 OFDT Cote : Classeur Permalink :
in New England Journal of Medicine > Vol.348, n°6 (February 6, 2003) . - 487-488[article]A community-based evaluation of sudden death associated with therapeutic levels of methadone / S. S. CHUGH in American Journal of Medicine (The), Vol.121, n°1 (January 2008)
Titre : A community-based evaluation of sudden death associated with therapeutic levels of methadone Titre traduit : (Une évaluation communautaire de la mort subite liée à des niveaux thérapeutique d'usage de méthadone) Type de document : Périodique Auteurs : S. S. CHUGH ; SOCOTEANU C. ; REINIER K. ; WALTZ J. ; JUI J. ; GUNSON K. Année de publication : 2008 Article en page(s) : 66-71 Note générale : Letter: Increased assessment and monitoring needed for patients receiving methadone, L. Merlo & M. Gold, American Journal of Medicine, 2008;121(5):e23 & Author's reply. Langues : Anglais (eng) Mots-clés : Thésaurus TOXIBASE
METHADONE ; EVALUATION ; MORT ; AUTOPSIE ; ETUDE PROSPECTIVE ; ARRET CARDIAQUE ; COEUR
Discipline : TRA Traitement et prise en charge / Treatment and care Résumé : BACKGROUND: Published case reports have associated the therapeutic use of methadone with the occasional occurrence of sudden cardiac death. Because of the established utility of this drug and with the eventual goal of enhancing safety of use, we performed a community-based study to evaluate this association. METHODS: During a 4-year period, we prospectively evaluated all patients who consecutively had sudden cardiac death and underwent investigation by the medical examiner in the metropolitan area of Portland, Ore. Case subjects of interest were those with a therapeutic blood level of methadone ( Domaine : Drogues illicites / Illicit drugs Refs biblio. : 32 Affiliation : Cardiac Arrhythmia Center, Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, USA Numéro Toxibase : 1302437 Centre Emetteur : 13 OFDT Cote : A03558 Permalink :
in American Journal of Medicine (The) > Vol.121, n°1 (January 2008) . - 66-71[article]Effets somatiques liés à la consommation de cannabis / M. MALLARET in Revue Toxibase, n°12 spécial Toxibase-Crips (Déc. 2003)
Titre : Effets somatiques liés à la consommation de cannabis Titre traduit : (Somatic pathologies related to cannabis consumption.) Type de document : Périodique Auteurs : M. MALLARET Année de publication : 2003 Article en page(s) : p.30-40 Note générale : Revue Toxibase, 2003, (n° spécial Toxibase-Crips, 12, Déc 2003), 30-40 Langues : Français (fre) Mots-clés : Thésaurus TOXIBASE
CANNABIS ; ARRET CARDIAQUE ; PATHOLOGIE ORGANIQUE ; APPAREIL RESPIRATOIRE ; APPAREIL CARDIOVASCULAIRE ; INTOXICATION ; SYSTEME ENDOCRINIEN ; SYSTEME IMMUNITAIRE
Discipline : PAT Pathologie organique / Organic pathology Domaine : Drogues illicites / Illicit drugs Refs biblio. : 62 Affiliation : CEIP, Grenoble
Numéro Toxibase : 207249 Centre Emetteur : 02 Coordonnateur Permalink :
in Revue Toxibase > n°12 spécial Toxibase-Crips (Déc. 2003) . - p.30-40[article]
207249.pdfAdobe Acrobat PDF
Low cigarette consumption and risk of coronary heart disease and stroke: Meta-analysis of 141 cohort studies in 55 study reports / A. HACKSHAW ; J. K. MORRIS ; S. BONIFACE ; J. L. TANG ; D. MILENKOVIC in British Medical Journal, Vol.360, n°8138 (27 January 2018)
Titre : Low cigarette consumption and risk of coronary heart disease and stroke: Meta-analysis of 141 cohort studies in 55 study reports Type de document : Périodique Auteurs : A. HACKSHAW ; J. K. MORRIS ; S. BONIFACE ; J. L. TANG ; D. MILENKOVIC Année de publication : 2018 Article en page(s) : j5855 Note générale : Editorial: Just one cigarette a day seriously elevates cardiovascular risk. Johnson K.C., BMJ 2018; 360(8138): j5855. Langues : Anglais (eng) Mots-clés : Thésaurus TOXIBASE
TABAC ; FACTEUR DE RISQUE ; COEUR ; APPAREIL CARDIOVASCULAIRE ; SEXE ; ARRET CARDIAQUE ; CONSOMMATION
Discipline : EPI Epidémiologie / Epidemiology Résumé : Objective: To use the relation between cigarette consumption and cardiovascular disease to quantify the risk of coronary heart disease and stroke for light smoking (one to five cigarettes/day).
Design: Systematic review and meta-analysis.
Data sources: Medline 1946 to May 2015, with manual searches of references.
Eligibility criteria for selecting studies Prospective cohort studies with at least 50 events, reporting hazard ratios or relative risks (both hereafter referred to as relative risk) compared with never smokers or age specific incidence in relation to risk of coronary heart disease or stroke.
Data extraction/synthesis: MOOSE guidelines were followed. For each study, the relative risk was estimated for smoking one, five, or 20 cigarettes per day by using regression modelling between risk and cigarette consumption. Relative risks were adjusted for at least age and often additional confounders. The main measure was the excess relative risk for smoking one cigarette per day (RR1_per_day-1) expressed as a proportion of that for smoking 20 cigarettes per day (RR20_per_day-1), expected to be about 5% assuming a linear relation between risk and consumption (as seen with lung cancer). The relative risks for one, five, and 20 cigarettes per day were also pooled across all studies in a random effects meta-analysis. Separate analyses were done for each combination of sex and disorder.
Results: The meta-analysis included 55 publications containing 141 cohort studies. Among men, the pooled relative risk for coronary heart disease was 1.48 for smoking one cigarette per day and 2.04 for 20 cigarettes per day, using all studies, but 1.74 and 2.27 among studies in which the relative risk had been adjusted for multiple confounders. Among women, the pooled relative risks were 1.57 and 2.84 for one and 20 cigarettes per day (or 2.19 and 3.95 using relative risks adjusted for multiple factors). Men who smoked one cigarette per day had 46% of the excess relative risk for smoking 20 cigarettes per day (53% using relative risks adjusted for multiple factors), and women had 31% of the excess risk (38% using relative risks adjusted for multiple factors). For stroke, the pooled relative risks for men were 1.25 and 1.64 for smoking one or 20 cigarettes per day (1.30 and 1.56 using relative risks adjusted for multiple factors). In women, the pooled relative risks were 1.31 and 2.16 for smoking one or 20 cigarettes per day (1.46 and 2.42 using relative risks adjusted for multiple factors). The excess risk for stroke associated with one cigarette per day (in relation to 20 cigarettes per day) was 41% for men and 34% for women (or 64% and 36% using relative risks adjusted for multiple factors). Relative risks were generally higher among women than men.
Conclusions: Smoking only about one cigarette per day carries a risk of developing coronary heart disease and stroke much greater than expected: around half that for people who smoke 20 per day. No safe level of smoking exists for cardiovascular disease. Smokers should aim to quit instead of cutting down to significantly reduce their risk of these two common major disorders.
Domaine : Tabac / Tobacco Sous-type de document : Méta-analyse / Meta-analysis ; Revue de la littérature / Literature review Refs biblio. : 126 Affiliation : Cancer Research UK and UCL Cancer Trials Centre, University College London, London, UK Lien : https://doi.org/10.1136/bmj.j5855 URL : Editorial: https://doi.org/10.1136/bmj.k167 Permalink :
in British Medical Journal > Vol.360, n°8138 (27 January 2018) . - j5855[article]Mémento : Prise en charge des urgences en contexte addictologique / N. BONNET ; D. MICHELS ; M. BARAUDPermalinkShort term impact of smoke-free legislation in England: retrospective analysis of hospital admissions for myocardial infarction / M. SIMS ; R. MAXWELL ; L. BAULD ; A. GILMORE in British Medical Journal, Vol.340, n°7760 (19 June 2010)PermalinkStroke in young adults who abuse amphetamines or cocaine: a population-based study of hospitalized patients / WESTOVER A. N.Permalink