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Documents disponibles dans cette catégorie (135)
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OEDT = EMCDDA ; M. EVANS-BROWN ; A. GALLEGOS ; R. CHRISTIE ; S. SOLA ; A. ALMEIDA ; R. JORGE ; J. DE MORAIS ; R. SEDEFOV | Lisbon : OEDT / EMCDDA | Rapid communication | 2018In this update from the EU Early Warning System, the EMCDDA aims to provide insights into what is happening with new psychoactive substances in Europe, based on data from the agency's early warning and risk-assessment activities. This report cov[...]Périodique
M. S. GOLD ; MELKER R. J. ; D. M. DENNIS ; T. E. MOREY ; L. K. BAJPAI ; R. POMM ; K. FROST-PINEDA | 2006ENGLISH : We have proposed a novel hypothesis regarding the potential role of occupational or second-hand exposure in physician substance use, abuse, and addiction. While only 5.6% of licensed physicians in Florida are anesthesiologists, nearl[...]Article : Périodique
J. N. PARK ; E. RASHIDI ; K. FOTI ; M. ZOOROB ; S. SHERMAN ; G. C. ALEXANDER |Background: U.S. research examining the illicit drug supply remains rare even though the information could help reduce overdoses. Relatively little is known regarding how often opioids are found in stimulants and whether temporal and geographic [...]Article : Périodique
Les terres de ce pays étaient jadis les leurs. Les peuples autochtones du Canada ont vécu la dépossession et l'ethnocide. Les livres d'histoire demeurent encore silencieux sur un si troublant constat, en dépit d'un processus de réconciliation en[...]Article : Périodique
SMIALEK J.E. ; B. LEVINE ; CHIN L. ; S. C. WU ; A. J. JENKINS |FRANÇAIS : En 1992, lors de dépistage de routine post-mortem, la présence de fentanyl a été identifiée 30 fois. La concentration sanguine du fentanyl allait de 2,2 à 100 µg/l. L'analyse des 30 cas identifiés montre que 25 des personnes décédée[...]Rapport
OEDT = EMCDDA ; J. MOUNTENEY ; M. EVANS-BROWN ; I. GIRAUDON | Lisbon : OEDT / EMCDDA | Technical reports | 2012The EMCDDA Trendspotter case study on Fentanyl in Europe was undertaken during September and October 2012. It culminated in an expert meeting in Lisbon on 9-10 October 2012. The aim of the study was to increase understanding of the availability [...]Article : Périodique
The US epidemic of overdose caused by the synthetic opioid could replay here, some commentators have suggested. Ingrid Torjesen investigates.Périodique
T. L. MARTIN ; WOODALL K. L. ; B. A. MCLELLAN | 2006In order to characterize fentanyl-related deaths in the province of Ontario, Canada, a retrospective study of all cases in which fentanyl was quantitated in blood was conducted for the time period between 2002 and 2004. A total of 112 fentanyl-r[...]Article : Périodique
FRANÇAIS : Le fentanyl, puissant analgésique utilisé en médication pré-anesthésique, est devenu une drogue d'abus populaire, notamment chez les professionnels de la santé. Le détournement des formes pharmaceutiques et la disponibilité d'analog[...]Rapport
Background: Fentanyl is a powerful synthetic and short-acting painkiller that is 50-100 times more potent than morphine, meaning that 1/10th of a gram of fentanyl is equivalent to between 5-10 g of morphine. It was first synthesized by Dr. Paul [...]Article : Périodique
Fentanyl is a synthetic opioid analgesic historically used as a pain reliever and an anaesthetic. Recent concerns have arisen around the illicit use of fentanyl and its analogues in a number of European countries, linked to their high potency an[...]Rapport
In November 2016, the EMCDDA and Europol examined the available information on a new psychoactive substance N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]-furan-2-carboxamide, commonly known as furanylfentanyl, through a joint assessment. Furanylf[...]Rapport
This publication presents the data and findings of the risk assessment on N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]furan-2-carboxamide (furanylfentanyl), carried out by the extended Scientific Committee of the EMCDDA on 23 May 2017. On the ba[...]Rapport
The Global SMART Update is designed to provide regular brief reports on emerging patterns and trends of the global synthetic drug situation. The current issue sheds light on the rapidly unfolding public health threat posed by extremely potent[...]Rapport
The Global SMART Update is designed to provide regular brief reports on emerging patterns and trends of the global synthetic drug situation. The current issue provides insight into the non-medical use of opioids, which presents a significant [...]Rapport
The Global SMART Update is designed to provide regular brief reports on emerging patterns and trends of the global synthetic drug situation. The current issue provides insight to how the expansion of the synthetic drugs market is driven by re[...]Rapport
The Global SMART Update is designed to provide regular brief reports on emerging patterns and trends of the global synthetic drug situation. The current opioid crisis is a far-reaching drug and public health policy issue affecting several geo[...]Livre
O. CORAZZA, Éditeur scientifique ; A. ROMAN-URRESTARAZU, Éditeur scientifique | London : Routledge | 2019Handbook of Novel Psychoactive Substances (NPS) provides a comprehensive overview of the challenges that clinicians face when dealing with NPS and discusses how the profile of patients and their socio-demographic characteristics frame the seriou[...]Rapport
FRANÇAIS : Comment répondre aux problèmes des héroïnomanes âgés ? Comment lutter contre les décès causés par le fentanyl et ses dérivés extrêmement puissants ? Comment prévenir les risques dus à la consommation d'alcool et de drogues lors des f[...]Article : Périodique
Michael Ashburn, MD, MPH, tells of a new black market in Philadelphia's Kensington neighborhood, which, compared with the city as a whole, has a significantly higher percentage of residents living in poverty and a significantly lower life expect[...]Rapport
British Columbia Centre on Substance Use | Vancouver, BC : BC Centre on Substance Use (BCCSU) | 2019In British Columbia, the fabric of society is fraying. The morgues are full of community members who have died of opioid overdoses as a result of fentanyl poisoning of the illicit drug supply. For the first time in recent history, the life expec[...]Article : Périodique
Heroin uncertainties: Exploring users' perceptions of fentanyl-adulterated and -substituted 'heroin'
Background: The US is experiencing an unprecedented opioid overdose epidemic fostered in recent years by regional contamination of the heroin supply with the fentanyl family of synthetic opioids. Since 2011 opioid-related overdose deaths in the [...]NouveautéArticle : Périodique
M. S. KRIEGER ; J. L. YEDINAK ; J. A. BUXTON ; M. LYSYSHYN ; E. BERNSTEIN ; J. D. RICH ; T. C. GREEN ; S. E. HADLAND ; B. D. L. MARSHALL |Background: Synthetic opioid overdose mortality among young adults has risen more than 300% in the USA since 2013, primarily due to the contamination of heroin and other drugs with illicitly manufactured fentanyl. Rapid test strips, which can be[...]Rapport
M. BALL ; R. BROADHURST ; H. TRIVEDI | Canberra : Australian Institute of Criminology | Statistical Bulletin, ISSN 2206-7302 | 2019This bulletin provides a snapshot of the sale and distribution of fentanyl and its analogues across several popular illicit darknet markets. Data collected daily from six darknet markets between 2 January and 23 February 2019 reveal the amount, [...]Article : Périodique
Fentanyls as a class of drug have pharmacological properties that make them more likely to lead to overdose than other opioids. In addition to high potency and rapid onset of respiratory depression, these drugs also induce respiratory muscle sti[...]Article : Périodique
In April 2023, the Taliban banned poppy cultivation and the trade of all narcotics. This caused a 95% reduction in opium production. Usually, that would be good news. But there is a substantial worry: synthetic opioids might fill the void left b[...]Périodique
A. I. L. BERENS ; A. J. VOETS ; DEMEDTS P. | 1996Plusieurs cas d'overdose consécutives à l'absorption de fentanyl ou d'analogues confectionnés clandestinement en laboratoire, ont été relevés en Europe.Article : Périodique
Background: Illicitly manufactured fentanyl and its analogues are appearing in countries throughout the world, often disguised as heroin or counterfeit prescription pills, with resulting high overdose mortality. Possible explanations for this ph[...]Article : Périodique
For nearly a century heroin has dominated the illegal opioid trade. The global supply of heroin is estimated to generate tens of billions of dollars in revenues a year and its illegal use has long been the source of many societal harms. The arri[...]Article : Périodique
FRANÇAIS : Présentation du cas d'un homme de 36 ans intoxiqué par inhalation, après chauffage, du contenu d'un patch de fentanyl (analgésique narcotique synthétique) ayant entraîné une dépression respiratoire sévère. De fortes doses de naloxon[...]Rapport
Bureau for International Narcotics and Law Enforcement Affairs | Washington, DC : U.S. Department of State | 2022The Department of State's International Narcotics Control Strategy Report (INCSR) - due to Congress March 1st annually - is prepared in accordance with §489 of the Foreign Assistance Act of 1961, as amended (the "FAA," 22 U.S.C. §2291). The INCS[...]Rapport
Bureau for International Narcotics and Law Enforcement Affairs | Washington, DC : U.S. Department of State | 2023While the public health crisis of COVID-19 and its concomitant effects on drug trafficking, control, and use abated in 2022, the crisis of substance use continued, though it did not intensify to the same degree as in the past two years. Provisio[...]Article : Périodique
L. B. COTTLER ; B. A. GOLDBERGER ; S. J. NIXON ; C. W. STRILEY ; E. BARENHOLTZ ; N. D. FITZGERALD ; S. M. TAYLOR ; J. J. PALAMAR |Deaths from fentanyl and from psychostimulants are increasing (Kariisa et al., 2019; O’Donnell et al., 2020) and new psychoactive substances (NPS) continue to emerge (US Drug Enforcement Administration [DEA], 2020). Methods of drug administratio[...]Article : Périodique
T. SEYLER ; I. GIRAUDON ; A. NOOR ; J. MOUNTENEY ; P. GRIFFITHS |This paper addresses the question of whether Europe is facing an opioid epidemic and utilises data from the European monitoring system on opioid use, harms and availability, to help assess the situation. Data sources covering the last decade on [...]Article : Périodique
F. R. LAMY ; R. DANIULAITYTE ; M. J. BARRATT ; U. LOKALA ; A. SHETH ; R. G. CARLSON |Background: The United States is facing a "triple wave" epidemic fueled by novel synthetic opioids. Cryptomarkets, anonymous marketplaces located on the deep web, play an increasingly important role in the distribution of illicit substances. Thi[...]Rapport
Cette publication propose aux professionnels les informations nécessaires pour un bon usage des médicaments antalgiques opioïdes, sous un format facile d'accès, mettant en valeur les connaissances et les actions qui en découlent.Rapport
The goal of treatment for opioid addiction or opioid use disorder (OUD) is remission of the disorder leading to lasting recovery. Recovery is a process of change through which individuals improve their health and wellness, live self-directed liv[...]Article : Périodique
J. TOURNEBIZE ; V. GIBAJA ; E. FRAUGER ; N. AUTHIER ; D. SEYER ; A. FRESSE ; P. GILLET ; L. JAVOT ; J. P. KAHN ; Réseau français d'addictovigilance |FRANÇAIS : Objectif : L'objectif de cette étude était de réaliser un état des lieux des usages, mésusages et des cas d'abus/dépendance avec les formes non injectables de fentanyl (forme de fentanyl transdermique et formes de fentanyl transmuque[...]Article : Périodique
V. R. GIBAJA ; J. TOURNEBIZE ; L. JAVOT ; A. DAVELUY ; J. P. KAHN |FRANÇAIS : Le fentanyl, analgésique opioïde de synthèse réservé à l'anesthésie jusqu'aux années 90, a vu ses indications et ses utilisations élargies avec le développement de formes non injectables : d'abord la forme transdermique en 1998 et, d[...]Rapport
This publication presents the data and findings of the risk assessment on 2-methoxy-N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]acetamide (methoxyacetylfentanyl), carried out by the extended Scientific Committee of the EMCDDA on 21 March 2018. O[...]Article : Périodique
FRANÇAIS : Antalgiques, traitements de substitution, antidote de l'overdose, les morphiniques sont nombreux et d'indications variées. Leur pharmacologie est complexe et très probablement non encore complètement élucidée. Les voies nociceptives,[...]Article : Périodique
FRANÇAIS : Les intoxications par les opioïdes représentent un risque majeur pour la santé publique partout dans le monde. Depuis les années 2000, surtout aux États-Unis, il est observé une explosion des overdoses aux opioïdes jusqu'au décès. Au[...]Article : Périodique
La crise des opioïdes qui frappe l'Amérique du Nord est sans précédent dans sa dimension. Certains des facteurs objectifs qui expliquent ce drame commencent à être identifiés, notamment au niveau de dysfonctionnements du système de santé américa[...]Article : Périodique
L. HIKIN ; P. R. SMITH ; E. RINGLAND ; S. HUDSON ; S. R. MORLEY |Background: Synthetic fentanyl analogues are highly potent opioid drugs which have no pharmaceutical use in humans. We detected the synthetic fentanyl analogues; carfentanil, butyryl fentanyl, fluorobutyrylfentanyl, furanylfentanyl, and alfentan[...]Article : Périodique
Community-based overdose prevention programs first emerged in the 1990’s and are now the leading public health intervention for overdose. Key elements of these programs are overdose education and naloxone distribution to people who use opioids a[...]NouveautéArticle : Périodique
Synthetic opioids (SO) are a major risk for public health across the world. These drugs can be divided into 2 categories, pharmaceutical and non-pharmaceutical fentanyls. A new generation of SO has emerged on the drug market since 2010. North Am[...]Article : Périodique
M. ALIAS-FERRI ; E. MARCHEI ; R. PACIFICI ; S. PICHINI ; M. PELLEGRINI ; C. PEREZ-MANA ; E. PAPASEIT ; R. MUGA ; F. FONSECA ; M. FARRE ; M. TORRENS |INTRODUCTION: New synthetic opioids (NSO), a class of new psychoactive substances (NPS), have recently emerged and pose an upcoming global public health challenge. The effects produced by NSO are similar to those from morphine, but they present [...]Article : Périodique
B. LOVRECIC ; M. LOVRECIC ; B. GABROVEC ; M. CARLI ; M. PACINI ; A. G. I. MAREMMANI ; I. MAREMMANI |Background: In the last decade there has been a progressive increase in the use of new psychoactive substances (NPSs) that are not yet under international control. In particular, novel synthetic opioids (NSOs) have reappeared on the recreational[...]Article : Périodique
On April 21, 2006, increases in overdoses were reported among illicit drug users in Camden, New Jersey, via the CDC Epidemic Information Exchange (Epi-X). This alert elicited reports of similar increases in overdoses in other parts of New Jersey[...]