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ETUDE RANDOMISEE |
Documents disponibles dans cette catégorie (226)
Article : Périodique
BACKGROUND: Many adolescents receive mentoring. There is no systematic review if mentoring prevents alcohol and drug use. OBJECTIVES: Assess effectiveness of mentoring to prevent adolescent alcohol/drug use. SEARCH METHODS: Cochrane CENTRAL [...]Article : Périodique
M. P. CARRIERI ; L. MICHEL ; C. LIONS ; J. COHEN ; M. VRAY ; M. MORA ; F. MARCELLIN ; B. SPIRE ; A. MOREL ; P. ROUX ; The Methaville Study Group |Objective: Methadone coverage is poor in many countries due in part to methadone induction being possible only in specialized care (SC). This multicenter pragmatic trial compared the effectiveness of methadone treatment between two induction mod[...]Article : Périodique
R. P. MATTICK ; C. BREEN ; J. KIMBER ; M. DAVOLI |Background: Methadone maintenance was the first widely used opioid replacement therapy to treat heroin dependence, and it remains the best-researched treatment for this problem. Despite the widespread use of methadone in maintenance treatment fo[...]Article : Périodique
A. SCHNEEGANS ; F. BOURGOGNON ; E. ALBUISSON ; R. SCHWAN ; M. ARFA ; L. POLLI ; M. MOULARD ; V. LAPREVOTE ; T. SCHWITZER |FRANÇAIS : Les approches basées sur la pleine conscience ont montré leur efficacité chez les patients atteints de troubles liés à la consommation de substances. La prévention des rechutes basée sur la pleine conscience (MBRP) intègre les pratiq[...]Article : Périodique
G. SMEDSLUND ; R. C. BERG ; K. T. HAMMERSTROM ; A. STEIRO ; K. A. LEIKNES ; H. M. DAHL ; K. KARLSEN |ENGLISH: BACKGROUND: There are 76.3 million people with alcohol use disorders worldwide and 15.3 million with drug use disorders. Motivational interviewing (MI) is a client-centred, semi-directive method for enhancing intrinsic motivation to ch[...]Article : Périodique
H. RIGTER ; C. E. HENDERSON ; I. PELC ; P. TOSSMANN ; O. PHAN ; V. HENDRIKS ; M. SCHAUB |Background: Noticing a lack of evidence-based programmes for treating adolescents heavily using cannabis in Europe, government representatives from Belgium, France, Germany, The Netherlands, and Switzerland decided to have U.S.-developed multidi[...]Article : Périodique
C. WERCH ; M. J. MOORE ; C. C. DICLEMENTE ; R. BLEDSOE ; E. JOBLI |The primary purpose of this study was to test the efficacy of a brief, multi-health behavior intervention integrating physical activity and alcohol use prevention messages for high school-aged adolescents. A total of 604 participants, 335 9th an[...]Périodique
R. Q. SKRABEK ; L. GALLMOVA ; K. ETHANS ; D. PERRY | 2008A randomized, double-blind, placebo-controlled trial was conducted to determine the benefit of nabilone in pain management and quality of life improvement in 40 patients with fibromyalgia. After a baseline assessment, subjects were titrated up o[...]Article : Périodique
N. LINTZERIS ; A. BHARDWAJ ; L. MILLS ; A. DUNLOP ; J. COPELAND ; I. MCGREGOR ; R. BRUNO ; J. GUGUSHEFF ; N. PHUNG ; M. MONTEBELLO ; T. CHAN ; A. KIRBY ; M. HALL ; M. JEFFERIES ; J. LUKSZA ; M. SHANAHAN ; R. KEVIN ; D. ALLSOP ; Agonist Replacement for Cannabis Dependence study group |ENGLISH: Importance: There are no effective medications for treating dependence on cannabis. Objective: To examine the safety and efficacy of nabiximols in the treatment of patients with cannabis dependence. Design, Setting, and Participants:[...]Article : Périodique
H. E. JONES ; K. KALTENBACH ; S. H. HEIL ; S. M. STINE ; M. G. COYLE ; A. M. ARRIA ; K. E. O'GRADY ; P. SELBY ; P. R. MARTIN ; G. FISCHER |Background: Methadone, a full mu-opioid agonist, is the recommended treatment for opioid dependence during pregnancy. However, prenatal exposure to methadone is associated with a neonatal abstinence syndrome (NAS) characterized by central nervou[...]Article : Périodique
N. WALKER ; V. PARAG ; M. VERBIEST ; G. LAKING ; M. LAUGESEN ; C. BULLEN |Background: Combination nicotine replacement therapy shows additive cessation benefits. We aimed to find out the effectiveness of combining nicotine patches with an e-cigarette (with and without nicotine) on six-month smoking abstinence. Method[...]Article : Périodique
L. F. STEAD ; R. PERERA ; C. BULLEN ; D. MANT ; T. LANCASTER |BACKGROUND: The aim of nicotine replacement therapy (NRT) is temporarily to replace much of the nicotine from cigarettes to reduce motivation to smoke and nicotine withdrawal symptoms, thus easing the transition from cigarette smoking to complet[...]Article : Périodique
A. WHITE ; D. KAVANAGH ; H. STALLMAN ; B. KLEIN ; F. KAY-LAMBKIN ; J. PROUDFOOT ; J. DRENNAN ; J. CONNOR ; A. BAKER ; E. HINES ; R. YOUNG |BACKGROUND: There has been a significant increase in the availability of online programs for alcohol problems. A systematic review of the research evidence underpinning these programs is timely. OBJECTIVES: Our objective was to review the effi[...]Article : Périodique
R. P. SCHWARTZ ; S. M. KELLY ; S. G. MITCHELL ; J. GRYCZYNSKI ; K. E. O'GRADY ; D. GANDHI ; Y. OLSEN ; J. H. JAFFE |Background and Aims: Methadone patients who discontinue treatment are at high risk of relapse, yet a substantial proportion discontinue treatment within the first year. We investigated whether a patient-centered approach to methadone treatment i[...]Périodique
R. S. GARFEIN ; E. T. GOLUB ; A. E. GREENBERG ; H. HAGAN ; D. L. HANSON ; S. M. HUDSON ; F. KAPADIA ; M. H. LATKA ; L. J. OUELLET ; D. W. PURCELL ; S. A. STRATHDEE ; H. THIEDE | 2007OBJECTIVES: To evaluate whether a behavioral intervention, which taught peer education skills, could reduce injection and sexual risk behaviors associated with primary HIV and hepatitis C virus infection (HCV) among young injection drug users (I[...]Article : Périodique
Objective: A small body of evidence supports targeting adolescents who are heavy users of cannabis with brief interventions, yet more research is needed to confirm the effectiveness of these studies. We conducted a secondary analysis of our Peer[...]Article : Périodique
Article : Périodique
BACKGROUND: Personality factors are implicated in the vulnerability to adolescent alcohol misuse. This study examined whether providing personality-targeted interventions in early adolescence can delay drinking and binge drinking in high-risk yo[...]Article : Périodique
A. E. PERRY ; M. NEILSON ; M. MARTYN-ST JAMES ; J. M. GLANVILLE ; R. WOODHOUSE ; C. GODFREY ; C. HEWITT |Background: The review represents one in a family of four reviews focusing on a range of different interventions for drug-using offenders. This specific review considers pharmacological interventions aimed at reducing drug use or criminal activi[...]Article : Périodique
A. ARAIN ; J. DE SOUSA ; K. CORTEN ; R. VERRANDO ; H. THIJS ; C. MATHEI ; F. BUNTINX ; G. ROBAEYS |Background: Treatment uptake for hepatitis C virus (HCV) infection remains low in persons who inject drugs (PWID), due to lack of knowledge and low perceived need for treatment. Therefore, we conducted a pilot study to assess the influence on kn[...]Article : Périodique
ENGLISH : Aims: To assess the feasibility of conducting an RCT comparing buprenorphine and methadone maintenance therapy in Norfolk. Design: Forty-two opiate dependent patients were given the option of being randomized or choosing between open[...]Article : Périodique
AIMS This study conducted a secondary analysis to examine injection cessation and decreasing frequency of injection during a multi-site randomized controlled HIV prevention intervention trial that sought to reduce sexual and injection risk behav[...]Article : Périodique
Young adults in college have high rates of marijuana use, abuse, and dependence. Web-based interventions are increasingly popular, but their dissemination exceeds empirical support. One popular but understudied program is The Marijuana eCHECKUP [...]Article : Périodique
BACKGROUND AND AIMS: The prevalence of cannabis use based on self-reports is likely to be underestimated in population surveys, especially in contexts where its use is a criminal offence. Indirect survey methods ask sensitive questions ensuring [...]Article : Périodique
There are many mandated school-based programs to prevent adolescent alcohol and drug (AOD) use, but few are voluntary and take place outside of class time. Objectives: This cluster randomized controlled trial evaluates CHOICE, a voluntary after[...]