A 10-year review of cannabis exposure in children under 3-years of age: do we need a more global approach? / I. CLAUDET ; M. LE BRETON ; C. BREHIN ; N. FRANCHITTO in European Journal of Pediatrics, Vol.176, n°4 (April 2017)

Donner un avis [article]  inEuropean Journal of Pediatrics > Vol.176, n°4 (April 2017) . - 553-556 Titre : A 10-year review of cannabis exposure in children under 3-years of age: do we need a more global approach? Type de document : Périodique Auteurs : I. CLAUDET ; M. LE BRETON ; C. BREHIN ; N. FRANCHITTO Année de publication : 2017 Article en page(s) : 553-556 Langues : Anglais (eng) Mots-clés : Thésaurus Géographique FRANCE Thésaurus TOXIBASE URGENCE ; ENFANT ; CANNABIS ; PEDIATRIE ; INTOXICATION ; EVOLUTION ; ETUDE RETROSPECTIVE ; TOXICOLOGIE ; TETRAHYDROCANNABINOL Discipline : PRO Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods Résumé : Pediatricians working in an emergency environment are confronted with children admitted to emergency departments for intoxication on a daily basis. We carried out a retrospective cohort study of children admitted to a pediatric emergency department due to unintentional cannabis exposure over a 10-year period from 2004 to 2014. Twenty-nine children under the age of 3 were admitted with a positive cannabis urine test. Eighty-seven percent of intoxications occurred at the family home. Resin was the main form of ingested cannabis (69%). The mean age was 16.5 +/- 5.2 months, and mean weight was 11.1 +/- 2.1 Kg. Sixty percent of admissions occurred between 2012 and 2014. More severe presentations, based on Poisoning Severity Score, occurred over the past 2 years. Four children experienced seizures before admission. Ten children (34%) had a decreased level of consciousness (GCS Domaine : Drogues illicites / Illicit drugs Refs biblio. : 13 Affiliation : Pediatric Emergency Department, Children hospital, CHU Toulouse, Toulouse, France Permalink : https://bdoc.ofdt.fr/index.php?lvl=notice_display&id=78874 [article]

10ème Congrès annuel de la SFTA et 6èmes Journées scientifiques du Centre de Compétence en Chimie et Toxicologie Analytiques. Résumés des communications orales et affichées / SFTA in Annales de Toxicologie Analytique, Vol.14, n°2 (2002)

Donner un avis [article]  inAnnales de Toxicologie Analytique > Vol.14, n°2 (2002) . - 135-162 Titre : 10ème Congrès annuel de la SFTA et 6èmes Journées scientifiques du Centre de Compétence en Chimie et Toxicologie Analytiques. Résumés des communications orales et affichées Titre traduit : (SFTA 10th annual meeting and CCCTA 6th scientific meeting. Abstracts of the communications.) Type de document : Périodique Auteurs : SFTA, Organisateur de réunion, de conférence Année de publication : 2002 Article en page(s) : 135-162 Note générale : STFA, Martigny (Suisse), 19-21 juin 2002, Annales de Toxicologie Analytique, 2002, 14, (2), 135-162 Langues : Français (fre) Mots-clés : Thésaurus TOXIBASE MEDICAMENTS ; PRODUIT DOPANT ; METHADONE ; BUPRENORPHINE ; BENZODIAZEPINES ; AMPHETAMINES ; COCAINE ; CANNABIS ; TOXICOLOGIE ; DEPISTAGE ; ANALYSE CHIMIQUE ; INTOXICATION ; CONDUITE DE VEHICULE ; DOPAGE ; MEDECINE LEGALE ; RECHERCHE Discipline : PRO Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods Résumé : Une cinquantaine de communications détaillent des travaux récents en toxicologie, parmi lesquels beaucoup sont consacrés aux méthodes d'analyse chimique et problèmes posés par la détection de drogues (cannabis, cocaïne), de produits dopants, des benzodiazépines ainsi que de méthadone et de buprénorphine. Domaine : Plusieurs produits / Several products Refs biblio. : 50 Affiliation : France. France. Numéro Toxibase : 206276 Centre Emetteur : 02 Coordonnateur Cote : Abonnement Permalink : https://bdoc.ofdt.fr/index.php?lvl=notice_display&id=54174 [article]

25B-NBOMe and its precursor 2C-B: modern trends and hidden dangers / I. PAPOUTSIS ; P. NIKOLAOU ; M. STEFANIDOU ; C. SPILIOPOULOU ; S. ATHANASELIS in Forensic Toxicology, Vol.33, n°1 (January 2015)

Donner un avis [article]  inForensic Toxicology > Vol.33, n°1 (January 2015) . - 1-11 Titre : 25B-NBOMe and its precursor 2C-B: modern trends and hidden dangers Type de document : Périodique Auteurs : I. PAPOUTSIS ; P. NIKOLAOU ; M. STEFANIDOU ; C. SPILIOPOULOU ; S. ATHANASELIS Année de publication : 2015 Article en page(s) : 1-11 Langues : Anglais (eng) Mots-clés : Thésaurus TOXIBASE TOXICOLOGIE ; DROGUES DE SYNTHESE ; PHARMACOLOGIE ; ANALYSE CHIMIQUE ; PREVALENCE ; TYPE D'USAGE ; MECANISME D'ACTION ; EFFET SECONDAIRE ; INTOXICATION ; ETUDE DE CAS Discipline : PRO Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods Résumé : Substituted phenethylamines are a class of designer drugs that hold a significant position in the drug abuse market. The most important substances within this class appear to be 4-bromo-2,5-dimethoxyphenethylamine (2C-B) and its novel derivative 2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25B-NBOMe). Intoxications related to 2C-B use are still recorded worldwide, despite the fact that its use and trafficking are banned in many countries. 25B-NBOMe is a highly potent 2C-B derivative that has invaded recently in the "drug arena" and is considered legal to possess and supply in many countries. This manuscript reviews all available information regarding chemistry, availability, pharmacology, and toxicology of 2C-B and 25B-NBOMe. The intoxication and fatal cases reported, as well as the current legislation of these drugs, are also presented. Domaine : Drogues illicites / Illicit drugs Refs biblio. : 79 Affiliation : Department of Forensic Medicine and Toxicology, Faculty of Medicine, National and Kapodistrian University of Athens, Athens, Greece Permalink : https://bdoc.ofdt.fr/index.php?lvl=notice_display&id=75623 [article]

2C-I-NBOMe, an "N-bomb" that kills with "Smiles". Toxicological and legislative aspects / P. NIKOLAOU ; I. PAPOUTSIS ; M. STEFANIDOU ; C. SPILIOPOULOU ; S. ATHANASELIS in Drug and Chemical Toxicology, Vol.38, n°1 (January 2015)  

Donner un avis [article]  inDrug and Chemical Toxicology > Vol.38, n°1 (January 2015) . - 113-119 Titre : 2C-I-NBOMe, an "N-bomb" that kills with "Smiles". Toxicological and legislative aspects Type de document : Périodique Auteurs : P. NIKOLAOU ; I. PAPOUTSIS ; M. STEFANIDOU ; C. SPILIOPOULOU ; S. ATHANASELIS Année de publication : 2015 Article en page(s) : 113-119 Langues : Anglais (eng) Mots-clés : Thésaurus TOXIBASE DROGUES DE SYNTHESE ; TOXICOLOGIE ; PHARMACOLOGIE ; LEGISLATION ; TYPE D'USAGE ; MECANISME D'ACTION ; EFFET SECONDAIRE ; INTOXICATION Discipline : PRO Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods Résumé : Substituted phenethylamines are a class of designer drugs that have recently emerged in the drug abuse market. Such substances remain legal to use, possess, and supply until these compounds become classified as scheduled. 2C-I-NBOMe or 25I-NBOMe is the N-benzyl-derivative of the iodo-substituted dimethoxy-phenethylamine (2C-I) that appeared recently in the drug market under the street name "N-Bomb". Due to its high potency, intoxications and fatal cases related to 2C-I-NBOMe use are increased worldwide. The use and trafficking of this substituted phenethylamine is banned only in some countries. A comprehensive review was performed using PubMed and Medline databases, together with additional non-peer reviewed information sources, including books and publications of state authorities in different countries, regarding chemistry, availability, pharmacology, and toxicology of 2C-I-NBOMe. Intoxications or lethal cases, published or reported, as well as the current legislation on this newly introduced drug are also reviewed. Domaine : Drogues illicites / Illicit drugs Sous-type de document : Revue de la littérature / Literature review Affiliation : Faculty of Medicine, Department of Forensic Medicine and Toxicology, National and Kapodistrian University of Athens, Athens, Greece Lien : http://dx.doi.org/10.3109/01480545.2014.911882 Permalink : https://bdoc.ofdt.fr/index.php?lvl=notice_display&id=76318 [article]

3,4-methylenedioxypyrovalerone (MDPV): chemistry, pharmacology and toxicology of a new designer drug of abuse marketed online / M. COPPOLA ; R. MONDOLA in Toxicology Letters, Vol.208, n°1 (5 January 2012)

Donner un avis [article]  inToxicology Letters > Vol.208, n°1 (5 January 2012) . - 12-15 Titre : 3,4-methylenedioxypyrovalerone (MDPV): chemistry, pharmacology and toxicology of a new designer drug of abuse marketed online Type de document : Périodique Auteurs : M. COPPOLA ; R. MONDOLA Année de publication : 2012 Article en page(s) : 12-15 Langues : Anglais (eng) Mots-clés : Thésaurus TOXIBASE DROGUES DE SYNTHESE ; CATHINONE ; INTERNET ; CHIMIE ; PHARMACOLOGIE ; TOXICOLOGIE Discipline : PRO Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods Résumé : The illicit marketplace of substances of abuse continually offers for sale legal alternatives to controlled drugs to a large public. In recent years, a new group of designer drugs, the synthetic cathinones, has emerged as a new trend, particularly among young people. The 3,4-methylenedioxypyrovalerone (MDPV), one of this synthetic compounds, caused an international alert for its cardiovascular and neurological toxicity. This substance, sold as bath salts, has caused many serious intoxications and some deaths in several countries. The aim of this paper is summarise the clinical, pharmacological and toxicological information about this new designer drug. HIGHLIGHTS: • 3,4-Methylenedioxypyrovalerone (MDPV) is a new designer drug of abuse. • This substance is marketed as bath salts. • MDPV is used as alternative to other illicit stimulants. • MDPV can produce neurological and cardiovascular toxicity. • Literature data suggest a high risk of acute toxicity, tolerance and dependence. Domaine : Drogues illicites / Illicit drugs Sous-type de document : Revue de la littérature / Literature review Affiliation : Department of Addiction, ASL CN2, Alba (CN), Italy Permalink : https://bdoc.ofdt.fr/index.php?lvl=notice_display&id=68695 [article]

A 3-year review of new psychoactive substances in casework / S. ELLIOTT ; J. EVANS in Forensic Science International, Vol.243 (October 2014)

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4,4'-DMAR: Chemistry, pharmacology and toxicology of a new synthetic stimulant of abuse / M. COPPOLA ; R. MONDOLA in Basic and Clinical Pharmacology and Toxicology, Vol.117, n°1 (July 2015)  

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4° congreso de la sociedad espanola de toxicomanias : "avances de la investigacion sobre drogodependencias", Valencia 25-27 de noviembre 1993 / ***

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4 Millions de francs pour la recherche sur le cannabis / MORJEAN M.

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5-(2-aminopropyl)indole: A new player in the drama of 'legal highs' alerts the community / M. KATSELOU ; I. PAPOUTSIS ; P. NIKOLAOU ; C. SPILIOPOULOU ; S. ATHANASELIS in Drug and Alcohol Review, Vol.34, n°1 (January 2015)

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5,6-Methylenedioxy-2-aminoindane: from laboratory curiosity to 'legal high' / C. T. GALLAGHER ; S. ASSI ; J. L. STAIR ; S. FERGUS ; O. CORAZZA ; J. M. CORKERY ; F. SCHIFANO in Human Psychopharmacology: Clinical and Experimental, Vol.27, n°2 (March 2012)

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A 6-year review of new psychoactive substances at the Centre antipoison Grand-Ouest d'Angers: Clinical and biological data / A. TURCANT ; M. DEGUIGNE ; S. FÉREC ; C. BRUNEAU ; I. LEBORGNE ; B. LELIÈVRE ; C. GEGU ; F. JEGOU ; C. ABBARA ; G. LE ROUX ; D. BOELS in Toxicologie Analytique et Clinique, Vol.29, n°1 (Février 2017)    

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A2 (N-benzylpiperazine) a new drug of abuse in Sweden / M. WIKSTROM

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About an unusual case: GC-MS detection of lidocaine / TEATINO

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L'abus de Daturas et de Kava en Nouvelle Calédonie : une pratique inquiétante / Y. BARGUIL ; S. MERMOND ; P. KINTZ ; M. VILLAIN ; E. CHOBLET ; V. CIRIMELE ; P. CABALION ; D. DUHET ; J. Y. CHARLOT in Annales de Toxicologie Analytique, Vol.18, n°1 (2006)

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