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| Titre : | Psychopharmacology, Vol.173, n°3-4. - May 2004 |
| Type de document : | Bulletin |
| Paru le : | 01/05/2004 |
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Article : Périodique
RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) is neurotoxic upon central serotonin systems in experimental animals and probably also in humans. Serotonin is involved in the habituation, sensitization and prepulse inhibition (PPI) [...]
Article : Périodique
RATIONALE: The effects of MDMA on driving behaviour are not clear, since the direct effects of MDMA on cognitive performance are reported as not generally negative. OBJECTIVES: To assess in an advanced driving simulator acute effects on simulate[...]
Article : Périodique
RATIONALE: Previous studies have presented conflicting findings regarding visuospatial span deficits in MDMA (`ecstasy') users, possibly attributable to a lack of distinction between simple visuospatial span and visuospatial working memory span.[...]
Article : Périodique
RATIONALE AND OBJECTIVES: The majority of experimental and clinical studies on the pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) tend to focus on its action on 5-HT biochemistry and function. However, there is considerable ev[...]
Article : Périodique
RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA or ecstasy) is a potent and selective serotonin neurotoxin whose use is growing among adolescents. Although cognitive deficits among adult MDMA users are well documented, little is known of the [...]
Article : Périodique
RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA or "ecstasy") causes serotonin neuron damage in laboratory animals. The serotonin system is known to be important in the regulation of mood. Previous research has shown that MDMA users score hig[...]
Article : Périodique
K. McCARDLE ;
S. LUEBBERS ;
J. D. CARTER ;
R. J. CROFT ;
C. STOUGH
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RATIONALE: It has been suggested that 3,4-methylenedioxymethamphetamine (MDMA or ecstasy) causes damage to the serotonergic system, and that this damage results in cognitive and mood impairments. OBJECTIVES: To examine the effect of chronic MDMA[...]
Article : Périodique
J. DAUMANN ;
G. HENSEN ;
B. THIMM ;
M. REZK ;
B. TILL ;
E. GOUZOULIS-MAYFRANK
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RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) has become a widely used recreational drug among young people. This is of great concern, since MDMA is neurotoxic in animal studies and its use has been associated with psychological d[...]
Article : Périodique
RATIONALE: The issue of ecstasy-related fatalities has extensively attracted the attention of both the media and the general public, but less so of the scientific literature. OBJECTIVES: The aim of the present review is to focus on the epidemiol[...]
Article : Périodique
RATIONALE: Neurotoxic effects of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on the serotonin (5-HT) system have been described in animals and humans, but little is known about long-term effects of ecstasy use on mood. OBJECTIVES: To inv[...]
Article : Périodique
RATIONALE: Establishing whether cognitive changes follow long-term use of MDMA ("ecstasy") in humans has been difficult because of possible confounds with other drug use, particularly cannabis. Convincing evidence may be only obtained using expe[...]
Article : Périodique
H. V. CURRAN ;
H. REES ;
T. HOARE ;
R. HOSHI ;
A. BOND
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RATIONALE: As central 5-hydroxytryptamine (5- HT) is attenuated for a period following a single dose of MDMA ("ecstasy") and low 5-HT is associated with aggression, then MDMA users may be more aggressive in the days following an acute dose of th[...]
Article : Périodique
M. FARRE ;
R. DE LA TORRE ;
B. O MATHUNA ;
P. N. ROSET ;
A. M. PEIRO ;
M. TORRENS ;
J. ORTUNO ;
M. PUJADAS ;
J. CAMI
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RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA, "ecstasy") is increasingly used by young people for its euphoric and empathic effects. MDMA presents non-linear pharmacokinetics, probably by inhibition of cytochrome P450 isoform 2D6. Users ar[...]
Article : Périodique
AIMS: Not every tablet sold as "ecstasy" contains MDMA (3,4-methylenedioxymethamphetamine). The historical origins and evolution of this mismatch will be reviewed, in order to estimate the proportions of ecstasy tablets containing MDMA at differ[...]
