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Psychopharmacology, Vol.173, n°3-4. - May 2004
| Titre : | Psychopharmacology, Vol.173, n°3-4. - May 2004 |
| Type de document : | Bulletin |
| Paru le : | 01/05/2004 |
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K. HEEKEREN ;
J. DAUMANN ;
M. A. GEYER ;
E. GOUZOULIS-MAYFRANK
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2004
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) is neurotoxic upon central serotonin systems in experimental animals and probably also in humans. Serotonin is involved in the habituation, sensitization and prepulse inhibition (PPI) [...]
K. A. BROOKHUIS ;
D. DE WAARD ;
N. SAMYN
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2004
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
RATIONALE: The effects of MDMA on driving behaviour are not clear, since the direct effects of MDMA on cognitive performance are reported as not generally negative. OBJECTIVES: To assess in an advanced driving simulator acute effects on simulate[...]
M. WAREING ;
P. N. MURPHY ;
J. E. FISK
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2004
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
RATIONALE: Previous studies have presented conflicting findings regarding visuospatial span deficits in MDMA (`ecstasy') users, possibly attributable to a lack of distinction between simple visuospatial span and visuospatial working memory span.[...]
M. I. COLADO ;
E. O'SHEA ;
A. R. GREEN
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2004
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
RATIONALE AND OBJECTIVES: The majority of experimental and clinical studies on the pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) tend to focus on its action on 5-HT biochemistry and function. However, there is considerable ev[...]
L. K. JACOBSEN ;
W. E. MENCL ;
K. R. PUGH ;
P. SKUDLARSKI ;
J. H. KRYSTAL
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2004
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA or ecstasy) is a potent and selective serotonin neurotoxin whose use is growing among adolescents. Although cognitive deficits among adult MDMA users are well documented, little is known of the [...]
J. P. ROISER ;
B. J. SAHAKIAN
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2004
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA or "ecstasy") causes serotonin neuron damage in laboratory animals. The serotonin system is known to be important in the regulation of mood. Previous research has shown that MDMA users score hig[...]
K. McCARDLE ;
S. LUEBBERS ;
J. D. CARTER ;
R. J. CROFT ;
C. STOUGH
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2004
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
RATIONALE: It has been suggested that 3,4-methylenedioxymethamphetamine (MDMA or ecstasy) causes damage to the serotonergic system, and that this damage results in cognitive and mood impairments. OBJECTIVES: To examine the effect of chronic MDMA[...]
J. DAUMANN ;
G. HENSEN ;
B. THIMM ;
M. REZK ;
B. TILL ;
E. GOUZOULIS-MAYFRANK
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2004
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) has become a widely used recreational drug among young people. This is of great concern, since MDMA is neurotoxic in animal studies and its use has been associated with psychological d[...]
RATIONALE: The issue of ecstasy-related fatalities has extensively attracted the attention of both the media and the general public, but less so of the scientific literature. OBJECTIVES: The aim of the present review is to focus on the epidemiol[...]
M. M. L. DE WIN ;
L. RENEMAN ;
J. B. REITSMA ;
G. J. DEN HEETEN ;
J. BOOIJ ;
W. VAN DEN BRINK
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2004
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
RATIONALE: Neurotoxic effects of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on the serotonin (5-HT) system have been described in animals and humans, but little is known about long-term effects of ecstasy use on mood. OBJECTIVES: To inv[...]
R. I. DAFTER ;
R. HOSHI ;
A. C. TALBOT
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2004
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
RATIONALE: Establishing whether cognitive changes follow long-term use of MDMA ("ecstasy") in humans has been difficult because of possible confounds with other drug use, particularly cannabis. Convincing evidence may be only obtained using expe[...]
H. V. CURRAN ;
H. REES ;
T. HOARE ;
R. HOSHI ;
A. BOND
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2004
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
RATIONALE: As central 5-hydroxytryptamine (5- HT) is attenuated for a period following a single dose of MDMA ("ecstasy") and low 5-HT is associated with aggression, then MDMA users may be more aggressive in the days following an acute dose of th[...]
M. FARRE ;
R. DE LA TORRE ;
B. O MATHUNA ;
P. N. ROSET ;
A. M. PEIRO ;
M. TORRENS ;
J. ORTUNO ;
M. PUJADAS ;
J. CAMI
|
2004
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique
RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA, "ecstasy") is increasingly used by young people for its euphoric and empathic effects. MDMA presents non-linear pharmacokinetics, probably by inhibition of cytochrome P450 isoform 2D6. Users ar[...]
AIMS: Not every tablet sold as "ecstasy" contains MDMA (3,4-methylenedioxymethamphetamine). The historical origins and evolution of this mismatch will be reviewed, in order to estimate the proportions of ecstasy tablets containing MDMA at differ[...]