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| Titre : | European Psychiatry, Vol.15, n°2. - March 2000 |
| Type de document : | Bulletin |
| Paru le : | 01/03/2000 |
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Epidemiologic studies in the general population and those based on the clinical assessment of schizophrenic populations have revealed a high degree of overlap between schizophrenia and addictive disorders. The abuse of psychoactive substances (i[...]
DUAUX E. ;
M. O. KREBS ;
H. LOO ;
M. F. POIRIER
|
2000
Dans European Psychiatry (Vol.15, n°2, March 2000) Article : Périodique
Dans European Psychiatry (Vol.15, n°2, March 2000) Article : Périodique
Addiction to various substances, including drugs and alcohol, probably arises from a combination of environmental and genetic factors. The genetic vulnerability to drug addiction is supported by several familial, adoption and twin studies. Howev[...]
Since 1990, association studies have amassed strong evidence implicating the D2 dopamine receptor (DRD2) gene in alcoholism. Specifically, the Taql A minor (A1) allele of the DRD2 gene has been associated with alcoholism. The DRD2 gene has also [...]
B. LE FOLL ;
J. C. SCHWARTZ ;
P. SOKOLOFF
|
2000
Dans European Psychiatry (Vol.15, n°2, March 2000) Article : Périodique
Dans European Psychiatry (Vol.15, n°2, March 2000) Article : Périodique
All drugs abused by humans increase dopamine in the shell of nucleus accumbens, which implicate the neurons of this structure in their hedonic and reinforcing properties. Among the various dopamine receptor subtypes, the D1 (D1R) and D3 (D3R) re[...]
M. LEJOYEUX ;
M. Mc LOUGHLIN ;
J. ADES
|
2000
Dans European Psychiatry (Vol.15, n°2, March 2000) Article : Périodique
Dans European Psychiatry (Vol.15, n°2, March 2000) Article : Périodique
The extension of the definition of dependence leads to the consideration of some impulsive disorders as a form of dependence disorder. This pathological condition is characterized by the repetitive occurrence of impulsive and uncontrolled behavi[...]