Buprenorphine treatment of opioid-dependent pregnant women: a comprehensive review

H. E. JONES ; S. H. HEIL ; A. BAEWERT ; A. M. ARRIA ; K. KALTENBACH ; P. R. MARTIN ; M. G. COYLE ; P. SELBY ; G. FISCHER | 2012
Dans Addiction (Vol.107, Suppl.1, November 2012) Article : Périodique

Aims: This paper reviews the published literature regarding outcomes following maternal treatment with buprenorphine in five areas: maternal efficacy, fetal effects, neonatal effects, effects on breast milk and longer-term developmental effects.[...]

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Neonatal abstinence syndrome after methadone or buprenorphine exposure

H. E. JONES ; K. KALTENBACH ; S. H. HEIL ; S. M. STINE ; M. G. COYLE ; A. M. ARRIA ; K. E. O'GRADY ; P. SELBY ; P. R. MARTIN ; G. FISCHER | 2010
Dans New England Journal of Medicine (Vol.363, n°24, December 9, 2010) Article : Périodique

Background: Methadone, a full mu-opioid agonist, is the recommended treatment for opioid dependence during pregnancy. However, prenatal exposure to methadone is associated with a neonatal abstinence syndrome (NAS) characterized by central nervou[...]

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