Drug interactions between opioids and antiretroviral medications : interaction between methadone, LAAM, and nelfinavir

E. F. McCANCE-KATZ ; RAINEY P. M. ; P. SMITH ; MORSE G. ; FRIEDLAND G. ; M. N. GOUREVITCH ; JATLOW P. | 2004
Périodique

ENGLISH : Understanding drug interactions between antiretrovirals and opiate therapies may decrease toxicities and enhance adherence, with improved HIV outcomes in injection drug users. We report results of a clinical pharmacology study design[...]

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Effect of opioid dependence pharmacotherapies on Zidovudine disposition

E. F. McCANCE-KATZ ; RAINEY P. M. ; FRIEDLAND G. ; T. R. KOSTEN ; JATLOW P. | 2001
Périodique

ENGLISH : Injection drug users are frequently infected with human immunodeficiency virus (HIV) and receive opioid dependence pharmacotherapies and Zidovudine (ZDV), the latter as a component of highly active antiretroviral therapy. We previous[...]

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The pharmacokinetics of methadone following co-administration with a lamivudine/zidovudine combination tablet in opiate-dependent subjects

RAINEY P. M. ; G. H. FRIEDLAND ; SNIDOW J. W. ; E. F. McCANCE-KATZ ; S. M. MITCHELL ; L. ANDREWS ; B. LANE ; JATLOW P. | 2002
Périodique

ENGLISH : Methadone pharmacokinetics were determined in an open-label, within subject study in 16 methadone-maintained, non-HIV-infected subjects prior to and following administration of one lamivudine 150-mg/zidovudine 300-mg combination tabl[...]

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