Dose-response effect of baclofen in reducing daily alcohol intake in alcohol dependence: secondary analysis of a randomized, double-blind, placebo-controlled trial

G. ADDOLORATO ; L. LEGGIO ; A. FERRULLI ; S. CARDONE ; G. BEDOGNI ; F. CAPUTO ; G. GASBARRINI ; R. LANDOLFI ; Baclofen Study Group | 2011
Dans Alcohol and Alcoholism (Vol.46, n°3, May-June 2011) Article : Périodique

AIMS: To explore the effect of baclofen in a dose of 20 mg three times per day, compared with the already studied dose of 10 mg three times per day, in the treatment of alcohol dependence. METHODS: We present a secondary analysis of a 12-week do[...]

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Neurobiochemical and clinical aspects of craving in alcohol addiction : a review

G. ADDOLORATO ; L. LEGGIO ; L. ABENAVOLI ; G. GASBARRINI | 2005
Périodique

ENGLISH : Craving plays an important role in the pathogenesis of alcohol dependence and relapse. In this review we have tried to analyse how many contrasting theories have been formulated in order to clarify the concept of craving. Many comple[...]

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