1-year retention and social function after buprenorphine-assisted relapse prevention treatment for heroin dependence in Sweden: a randomised, placebo-controlled trial

J. KAKKO ; K. D. SVANBORG ; M. J. KREEK ; M. HEILIG | 2003
Dans Lancet (The) (Vol.361, n°9358, February 22, 2003) Article : Périodique

Background: The partial opiate-receptor agonist buprenorphine has been suggested for treatment of heroin dependence, but there are few long-term and placebo-controlled studies of its effectiveness. We aimed to assess the 1-year efficacy of bupre[...]

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A stepped care strategy using buprenorphine and methadone versus conventional methadone maintenance in heroin dependence: a randomized controlled trial

J. KAKKO ; GRÖNBLADH L. ; K. D. SVANBORG ; J. VON WACHENFELDT ; RÜCK C. ; RAWLINGS B. ; NILSSON L. H. ; M. HEILIG | 2007
Dans American Journal of Psychiatry (Vol.164, n°5, May 2007) Article : Périodique

OBJECTIVE: Both methadone and buprenorphine are effective therapy for heroin dependence. Efficacy is best documented for methadone maintenance therapy, but safety concerns limit its use. Buprenorphine offers lower overdose risk and improved acce[...]

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