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Périodique
A. ELKASHEF ; F. VOCCI | 2003ENGLISH : The search for effective medications for cocaine addiction has been elusive. The failure to find such medications so far could be due to poor understanding of the underlying biology both in the premorbid condition and following the d[...]
Périodique
LEIDERMAN D. B. ; S. SHOPTAW ; A. MONTGOMERY ; D. A. BLOCH ; A. ELKASHEF ; LOCASTRO J. ; F. VOCCI | 2005ENGLISH : Aim : Development of effective medications for the treatment of cocaine dependence remains a major priority for the National Institute on Drug Abuse (NIDA) at the National Institutes of Health. The Cocaine Rapid Efficacy Screening Tr[...]
Périodique
K. M. KAMPMAN ; LEIDERMAN D. ; T. HOLMES ; LOCASTRO J. ; D. A. BLOCH ; M. A. REID ; S. SHOPTAW ; M. A. MONTGOMERY ; T. M. WINHUSEN ; SOMOZA E. C. ; D. A. CIRAULO ; A. ELKASHEF ; F. VOCCI | 2005ENGLISH : Aims : The Cocaine Rapid Efficacy Screening Trials (CREST) were designed by the National Institute on Drug Abuse Division of Treatment Research and Development (NIDA, DT R&D) to rapidly screen a number of medications potentially usef[...]
Périodique
D. A. CIRAULO ; O. SARID-SEGAL ; C. M. KNAPP ; A. M. CIRAULO ; LOCASTRO J. ; D. A. BLOCH ; M. A. MONTGOMERY ; LEIDERMAN D. B. ; A. ELKASHEF | 2005ENGLISH : Aims : The two studies presented here were conducted to assess the efficacy of paroxetine, pentoxifylline, riluzole, venlafaxine and pramipexole as medications for the treatment of cocaine dependence. Design : A multi-arm, modified b[...]
Article : Périodique
F. J. VOCCI ; J. ACRI ; A. ELKASHEF |In 1989, the National Institute on Drug Abuse (NIDA) established its Medications Development Program. This program has concentrated on developing pharmacotherapies for opiate and cocaine dependence and, more recently, for methamphetamine and can[...]
Périodique
S. P. BERGER ; T. M. WINHUSEN ; SOMOZA E. C. ; J. M. HARRER ; MEZINSKIS J. P. ; LEIDERMAN D. B. ; M. A. MONTGOMERY ; R. J. GOLDSMITH ; D. A. BLOCH ; SINGAL B. M. ; A. ELKASHEF | 2005ENGLISH : Aims : To conduct a preliminary evaluation of the safety and efficacy of reserpine, gabapentin or lamotrigine versus an unmatched placebo control as a treatment for cocaine dependence. Design : A 10-week out-patient study using the C[...]
Périodique
T. M. WINHUSEN ; SOMOZA E. C. ; J. M. HARRER ; MEZINSKIS J. P. ; M. A. MONTGOMERY ; R. J. GOLDSMITH ; F. S. COLEMAN ; D. A. BLOCH ; LEIDERMAN D. B. ; SINGAL B. S. ; P. BERGER ; A. ELKASHEF | 2005ENGLISH : Aims : To conduct a preliminary evaluation of the safety and efficacy of tiagabine, sertraline or donepezil versus an unmatched placebo control as a treatment for cocaine dependence. Design : A 10-week out-patient study was conducted[...]
Périodique
A. ELKASHEF ; T. H. HOLMES ; D. A. BLOCH ; S. SHOPTAW ; K. KAMPMAN ; M. S. REID ; SOMOZA E. ; D. CIRAULO ; J. ROTROSEN ; LEIDERMAN D. ; A. MONTGOMERY ; F. VOCCI | 2005ENGLISH : Aim : To analyze pooled data from the Cocaine Rapid Evaluation Screening Trial (CREST). Pooling data from these small pilot trials into four major drug classes permitted data exploration for treatment and covariate effects with incre[...]
