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Périodique
M. A. HUESTIS ; J. E. HENNINGFIELD ; E. J. CONE | 1992delta 9-Tetrahydrocannabinol (THC), the primary psychoactive constituent of marijuana, is rapidly transferred from lungs to blood during smoking. Oxidative metabolism of THC yields the active metabolite, 11-hydroxy-delta 9-tetrahydrocannabinol ([...]
Périodique
M. L. COPERSINO ; S. J. BOYD ; TASHKIN D. P. ; M. A. HUESTIS ; S. J. HEISHMAN ; DERMAND J. C. ; SIMMONS M. S. ; D. A. GORELICK | 2006ENGLISH : This study investigates the clinical significance of a cannabis withdrawal syndrome in 104 adult, non-treatment-seeking, primarily cannabis users who reported at least one serious attempt to stop using cannabis. Retrospective self-re[...]
Article : Périodique
This study examined trajectories of smoking during pregnancy among low-income smokers and differences on demographics, psychopathology, and smoking outcome expectancies among women with different smoking trajectories. The sample consisted of 215[...]
Article : Périodique
Controlled cannabis vaporizer administration: Blood and plasma cannabinoids with and without alcohol
R. L. HARTMAN ; T. L. BROWN ; G. MILAVETZ ; A. SPURGIN ; D. A. GORELICK ; G. GAFFNEY ; M. A. HUESTIS |ENGLISH: BACKGROUND: Increased medical and legal cannabis intake is accompanied by greater use of cannabis vaporization and more cases of driving under the influence of cannabis. Although simultaneous Delta9-tetrahydrocannabinol (THC) and alcoh[...]![Deterring driving under the influence of cannabis [Editorial]](https://bdoc.ofdt.fr/thumbnail.php?type=1&id=76420)
Article : Périodique
Cannabis use may increase with widening legalization and approval for medical use. With evidence that cannabis use increases accident risk, but can be detected in biological fluids in the absence of impairment, societies face complex challenges [...]
Article : Périodique
M. J. BAGGOTT ; K. J. GARRISON ; J. R. COYLE ; G. P. GALLOWAY ; A. J. BARNES ; M. A. HUESTIS ; J. E. MENDELSON |Entactogens such as 3,4-Methylenedioxymethamphetamine (MDMA, "molly", "ecstasy") appear to have unusual, potentially therapeutic, emotional effects. Understanding their mechanisms can benefit from clinical experiments with related drugs. Yet the[...]
Article : Périodique
T. D. MARCOTTE ; A. UMLAUF ; D. J. GRELOTTI ; E. G. SONES ; K. F. MASTROPIETRO ; R. T. SUHANDYNATA ; M. A. HUESTIS ; I. GRANT ; R. L. FITZGERALD |Key Points: Question: How accurate are field sobriety tests (FSTs) in identifying acute Delta9-tetrahydrocannabinol (THC) impairment? Findings: In this randomized clinical trial of 184 cannabis users randomized to THC or placebo, law enforceme[...]
Périodique
R. E. CHOO ; M. A. HUESTIS ; J. R. SCHROEDER ; A. S. SHIN ; H. E. JONES | 2004ENGLISH : Maternal tobacco consumption during pregnancy has been associated with lower birth weight infants, preterm births, intrauterine growth retardation, smaller head circumference and increase in morbidity, yet few studies have examined t[...]
Périodique
Recent marijuana blunt smoking impacts carbon monoxide as a measure of adolescent tobacco abstinence
E. T. MOOLCHAN ; D. ZIMMERMAN ; SEHNERT S. S. ; M. A. HUESTIS ; D. H. EPSTEIN | 2005ENGLISH : Adolescent tobacco smokers have a higher prevalence of marijuana (MJ) smoking than adolescents who do not smoke tobacco. As part of an adolescent smoking cessation trial, we examined whether MJ smoking, and specifically blunt (gutted[...]
Article : Périodique
B. K. LOGAN ; A. L. A. MOHR ; M. FRISCIA ; A. J. KROTULSKI ; D. M. PAPSUN ; S. L. KACINKO ; J. D. ROPERO-MILLER ; M. A. HUESTIS |Novel psychoactive substances (NPS) represent significant analytical and interpretive challenges to forensic and clinical toxicologists. Timely access to case reports and reports of adverse incidents of impairment or toxicity is imperative to cl[...]
Article : Périodique
M. A. HUESTIS ; S. J. BOYD ; S. J. HEISHMAN ; K. L. PRESTON ; D. BONNET ; G. LE FUR ; D. A. GORELICK |RATIONALE: A single 90-mg dose of the cannabinoid CB1 receptor antagonist rimonabant attenuates effects of smoked cannabis in humans. OBJECTIVES: The objective of this study is to evaluate whether repeated daily 40-mg doses of rimonabant can att[...]
Périodique
S. J. BOYD ; TASHKIN D. P. ; M. A. HUESTIS ; S. J. HEISHMAN ; DERMAND J. C. ; SIMMONS M. S. ; D. A. GORELICK | 2005FRANÇAIS : Article traduit dans la revue Alcoologie et Addictologie, 2004, 26, (4), 323-326 ENGLISH : This study examines self-reported quitting strategies used by adult, non-treatment-seeking marijuana smokers. Sixty-five subjects rated the [...]
Article : Périodique
S. J. BOYD ; TASHKIN D. P. ; M. A. HUESTIS ; S. J. HEISHMAN ; DERMAND J. C. ; SIMMONS M. S. ; D. A. GORELICK |FRANÇAIS : Ce travail étudie les stratégies mises au point par les adultes fumeurs de cannabis qui ne sont pas demandeurs d'un traitement. 65 patients ont coté la manière dont ils utilisaient ces 13 méthodes différentes et leur efficacité. Ils[...]
Article : Périodique
R. A. GUSTAFSON ; B. LEVINE ; P. R. STOUT ; K. L. KLETTE ; M. P. GEORGE ; E. T. MOOLCHAN ; M. A. HUESTIS |BACKGROUND: Urinary cannabinoid excretion and immunoassay performance were evaluated by semiquantitative immunoassay and gas chromatography-mass spectrometry (GC/MS) analysis of metabolite concentrations in 4381 urine specimens collected before,[...]
Périodique
M. A. HUESTIS ; E. J. CONE | 1998The excretion of marijuana metabolites occurs over an extended period of time, yet few studies have been designed for accurate estimation of excretion half-lives. The authors monitored excretion of the primary urinary metabolite of marijuana, 11[...]
