Titre : | Quality of life among alcohol-dependent patients: How satisfactory are the available instruments? A systematic review (2012) |
Auteurs : | A. LUQUIENS ; M. REYNAUD ; B. FALISSARD ; H. J. AUBIN |
Type de document : | Article : Périodique |
Dans : | Drug and Alcohol Dependence (Vol.125, n°3, October 2012) |
Article en page(s) : | 192-202 |
Langues: | Anglais |
Discipline : | TRA (Traitement et prise en charge / Treatment and care) |
Mots-clés : |
Thésaurus mots-clés ALCOOL ; DEPENDANCE ; ALCOOLIQUE ; QUALITE DE VIE ; ETUDE CLINIQUE ; CONCEPT |
Résumé : |
Aim: The purpose of this systematic review was to compare quality-of-life instruments used as outcome measures in randomized clinical trials for alcohol-dependence treatment.
Methods: Randomized controlled clinical trials, indexed in the EMBASE, PubMed and PsycINFO databases since 1981, which aimed at improving the quality of life in alcohol-dependent patients and used as instrument to measure the quality of life, as specifically designated by the authors, were included. Results: Of the 331 articles screened, 18 studies were included in the review. Eight different quality-of-life instruments were used as outcome measures. Twenty-seven life domains were explored. Between-scale heterogeneity was high. The scale most frequently used was the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). Only 1 clinical trial demonstrated a significant difference between intervention groups at all endpoints, using the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q). Conclusion: Because many different instruments were used, it is difficult to compare quality-of-life improvement between trials. The most frequently used instrument was a generic health status measure that may not be well suited as a quality-of-life measure for subjects with alcohol dependence. The construction and validation of a specific patient-reported outcome based on alcohol-dependent patients' concerns would effectively contribute to the assessment of treatment efficacy. |
Domaine : | Alcool / Alcohol |
Sous-type de document : | Revue de la littérature / Literature review |
Affiliation : | Hôpital Paul Brousse, Univ. Paris-Sud, INSERM U669, Villejuif, France |
Cote : | Abonnement |
Accueil