Titre : | Neuropsychiatric consequences (atypical psychosis and complex-partial seizures) of ecstasy use: possible evidence for toxicity-vulnerability predictors and implications for preventative and clinical care (2003) |
Auteurs : | M. VECELLIO ; SCHOPPER C. ; MODESTIN J. H. C. |
Type de document : | Article : Périodique |
Dans : | Journal of Psychopharmacology (Vol.17, n°3, 2003) |
Article en page(s) : | 163-167 |
Langues: | Anglais |
Discipline : | PSY (Psychopathologie / Psychopathology) |
Mots-clés : |
Thésaurus mots-clés ETUDE DE CAS ; TROUBLE BIPOLAIRE ; EPILEPSIE ; MDMA-ECSTASY ; PSYCHOSE ; PARANOIA ; NEUROPSYCHIATRIE ; TOXICITE ; FACTEUR DE VULNERABILITEThésaurus géographique SUISSE |
Résumé : | Two case reports of ecstasy abuse and its serious neuropsychiatric complications are presented. The first patient developed a florid paranoid psychosis resembling schizophrenia after repeated long-term recreational ecstasy abuse, and significant alterations with intermittent paroxysmal discharges were found in his electroencephalogram. The second patient showed an atypical paranoid psychosis with Fregoli syndrome and a series of complex-partial epileptic seizures with secondary generalization after a first single ecstasy dose. Both subjects presented considerable vulnerability; the first a minimal brain dysfunction after perinatal asphyxia and a persisting attention deficit/hyperactivity disorder, the second a long-lasting opioid addiction. In vulnerable individuals, dose-independent ecstasy abuse can lead to unpredictable and potentially dangerous neuropsychiatric sequelae which require proper initial assessment and adequate treatment. |
Domaine : | Drogues illicites / Illicit drugs |
Affiliation : |
Psychiatric University Hospital Zurich, Zürich Suisse. Switzerland. |
Centre Emetteur : | 13 OFDT |
Cote : | A01875 |
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