Titre : | Cannabis use and the risk of later schizophrenia : a review |
Titre traduit : | (Usage de cannabis et risque de schizophrénie consécutive. Etude de synthèse) |
Auteurs : | P. SMIT ; L. BOLIER ; P. CUIJPERS |
Type de document : | Périodique |
Année de publication : | 2004 |
Format : | 425-430 / tabl. |
Note générale : |
Addiction, 2004, 99, (4), 425-430 |
Langues: | Anglais |
Discipline : | PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods) |
Mots-clés : |
Thésaurus mots-clés CANNABIS ; TROUBLE BIPOLAIRE ; SCHIZOPHRENIE ; PSYCHOSE ; AUTOMEDICATION ; EFFET SECONDAIRE ; FACTEUR DE VULNERABILITE ; POPULATION A RISQUE ; ETIOLOGIE |
Résumé : |
FRANÇAIS : Examen de 5 études longitudinales ayant étudié la relation entre usage de cannabis et expérience consécutive de symptômes psychotiques ayant nécessité une hospitalisation lors de laquelle le diagnostic de schizophrénie a pu être confirmé. ENGLISH : Aim : To study the role of cannabis use in the onset of symptoms and disorders in the schizophrenia spectrum. Design : Review of five population-based, longitudinal studies on the relationship between cannabis use and problems ranging from the experience of psychotic symptoms to hospitalization with a confirmed diagnosis of schizophrenia. Several hypotheses are examined that may explain this relationship : (1) self medication ; (2) effects of other drugs ; (3) confounding ; (4) stronger effect in predisposed people, and (5) etiological hypothesis. Findings : Hypotheses 1 and 2 can be dismissed ; hypothesis 3 is still open to debate, and converging evidence is found for hypotheses 4 and 5 - antecedent cannabis use appears to act as a risk factor in the onset of schizophrenia, especially in vulnerable people, but also in people without prior history. Conclusion : There is an intrinsic message here for public health, but how that message is to be translated into action is not immediately clear. (Review' s abstract) |
Note de contenu : | tabl. |
Domaine : | Drogues illicites / Illicit drugs |
Sous-type de document : | Etude de synthèse / Synthetic study |
Refs biblio. : | 22 |
Affiliation : |
Trimbos Inst., PO Box 725, 3500 AS Utrecht ; fsmittrimbo.nl Norvège. Norway. |
Numéro Toxibase : | 207418 |
Centre Emetteur : | 02 Coordonnateur |
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