Titre : | Substance use and other psychiatric disorders in first-degree relatives of opioid-dependent males: a casecontrolled study from India |
Titre traduit : | (Consommation de substances et autres troubles psychiatriques chez les parents au premier degré d'hommes dépendants des opioïdes : une étude de cas contrôlés en Inde.) |
Auteurs : | M. P. PRASANT ; S. K. MATTOO ; D. BASU |
Type de document : | Périodique |
Année de publication : | 2006 |
Format : | 413-419 / tabl. |
Note générale : |
Addiction, 2006, 101, (3), 413-419, tabl.
|
Langues: | Anglais |
Discipline : | EPI (Epidémiologie / Epidemiology) |
Mots-clés : |
Thésaurus mots-clés OPIOIDES ; FAMILLE ; CONSOMMATION ; PSYCHOPATHOLOGIE ; ETUDE DE CAS ; EPIDEMIOLOGIE DESCRIPTIVEThésaurus géographique INDE |
Résumé : | Aim: To assess the prevalence of substance use and other psychiatric disorders in first-degree relatives of males with opioid dependence compared to normal controls. Design: Observational, casecontrol study using family history method. Setting: A drug addiction treatment centre in northern India. Participants: First-degree relatives of 100 male probands with opioid dependence and no comorbidity (n = 493) and those of 50 matched probands from normal population (n = 254). Measurement: Family interview of probands and family members, using the Family Interview for Genetic Studies. The main outcome measure was relative risk (expressed as odds ratio after controlling for confounding variables using logistic regression) of familial aggregation of psychiatric and substance use disorders. Findings: First-degree relatives of opioid-dependent males were more likely to have a psychiatric disorder than those of normal controls [adjusted odds ratio (OR) 4.47; 95% confidence interval (CI) 1.9710.11; P |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 29 |
Affiliation : |
Department of Psychiatry, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh -160012. Inde. India. |
Numéro Toxibase : | 208840 |
Centre Emetteur : | 02 Coordonnateur |
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