|Titre :||Cannabis use increases the risk of sickness absence: Longitudinal analyses from the CONSTANCES cohort (2022)|
|Auteurs :||A. DEGUILHEM ; A. LECLERC ; M. GOLDBERG ; C. LEMOGNE ; Y. ROQUELAURE ; M. ZINS ; G. AIRAGNES|
|Type de document :||Article : Périodique|
|Dans :||Frontiers in Public Health (Vol.10, 2022)|
|Article en page(s) :||art. 869051|
|Discipline :||EPI (Epidémiologie / Epidemiology)|
Thésaurus TOXIBASECOHORTE ; CANNABIS ; ABSENTEISME ; FACTEUR DE RISQUE ; ETUDE LONGITUDINALE ; MEDECINE DU TRAVAIL ; MILIEU PROFESSIONNEL ; ETUDE PROSPECTIVE
AIMS: To examine the longitudinal associations between cannabis use and risks of short (<7 days), medium (7-28 days), and long (>28 days) sickness absences at one-year follow-up.
METHODS: 87,273 participants aged 18-65 years from the French CONSTANCES cohort reported their frequency of cannabis use at inclusion between 2012 and 2018. Sickness absences occurring during one year of follow-up were collected from national medico-administrative registries. Multivariable generalized linear regressions were used to compute the Odds Ratios (OR) with their 95% Confidence Intervals (CI) of having at least one sickness absence at follow-up compared to no sickness absence, while controlling for sociodemographic factors, chronic conditions and occupational factors.
RESULTS: Cannabis use more than once a month was associated with an increased risk of short (OR, [95% CI]: 1.56 [1.32-1.83]) and medium (1.29 [1.07-1.54]) sickness absences at one-year follow-up, with dose-dependent relationships for short sickness absences (1.13 [1.08-1.18], p-for-trend <0.001). In stratified analyses, cannabis use was associated with an increased risk of sickness absences in older individuals, men, participants with good self-rated health, living or having lived as a couple, and having an open-ended contract.
CONCLUSIONS: Cannabis use prospectively increased the risk of short and medium sickness absences, even from once a month and with a dose-dependent relationship for short sickness absences. These findings should be considered in information and prevention public health campaigns to alert the general population and workers to this increased risk.
|Domaine :||Drogues illicites / Illicit drugs|
|Affiliation :||INSERM, Population-based Epidemiological Cohorts Unit, UMS 011, Villejuif, France|