Titre : | The evolving drug epidemic of prescription opioid injection and its association with HCV transmission among people who inject drugs in Montreal, Canada (2019) |
Auteurs : | J. BRUNEAU ; N. ARRUDA ; G. ZANG ; D. JUTRAS-ASWAD ; E. ROY |
Type de document : | Article : Périodique |
Dans : | Addiction (Vol.114, n°2, February 2019) |
Article en page(s) : | 366-373 |
Langues: | Anglais |
Discipline : | MAL (Maladies infectieuses / Infectious diseases) |
Mots-clés : |
Thésaurus géographique CANADAThésaurus mots-clés OPIOIDES ; INJECTION ; HEPATITE ; INCIDENCE ; EVOLUTION ; USAGER ; ETUDE PROSPECTIVE ; SEROPOSITIVITE ; INFECTION |
Résumé : |
AIMS: To examine temporal trends in prescription opioid (PO) injection and to assess its association with hepatitis C virus (HCV) seroconversion among people who inject drugs (PWID).
DESIGN: Prospective cohort study spanning 2004 to 2016. SETTING: Montreal, Canada. PARTICIPANTS: PWID reporting injection during the past 6 months. MEASUREMENTS: PWID were recruited between 2004 and 2016. At each 3-6-month follow-up visit, participants completed interview-administered questionnaires and were tested for HCV-antibody. FINDINGS: Among 1524 PWID [83% males, mean age 38 years, standard deviation (SD) = 10, 34% (31-36) prescription opioid (PO) injection past month] included in trends analyses, PO injection use expanded between 2004 and 2009, and plateaued between 2010 and 2016 (trend tests CONCLUSION: Prescription opioid injection increased among people who inject drugs in Montreal, Canada from 2004 to 2009, to reach a plateau between 2010 and 2016. The association between prescription opioid injection and HCV seroconversion was stronger during the second period than the first according to the epidemic phase. |
Domaine : | Autres substances / Other substances ; Drogues illicites / Illicit drugs |
Refs biblio. : | 33 |
Affiliation : | Research Center, Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada |
Cote : | Abonnement |
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