|Titre :||Prenatal alcohol exposure and offspring mental health: A systematic review (2019)|
|Auteurs :||K. E. EASEY ; M. L. DYER ; N. J. TIMPSON ; M. R. MUNAFO|
|Type de document :||Article : Périodique|
|Dans :||Drug and Alcohol Dependence (Vol.197, April 2019)|
|Article en page(s) :||344-353|
|Discipline :||EPI (Epidémiologie / Epidemiology)|
Thésaurus TOXIBASEALCOOL ; GROSSESSE ; SYNDROME D'ALCOOLISATION FOETALE ; SANTE MENTALE ; ANXIETE ; PSYCHOPATHOLOGIE ; TROUBLES EMOTIONNELS ; ENFANT D'USAGER ; TROUBLES DU COMPORTEMENT
Background: High levels of alcohol use in pregnancy have been shown to be associated with negative physical health consequences in offspring. However, the literature is less clear on the association of alcohol use in pregnancy and offspring mental health, specifically for low levels of prenatal alcohol exposure. We conducted a systematic review to evaluate studies examining this association.
Methods: Studies were identified by searching PsycINFO, PubMed and Web of Science, and were included if they examined alcohol use during pregnancy as an exposure and offspring mental health at age 3 or older as an outcome. We excluded non-English language publications and studies of fetal alcohol syndrome.
Results: Thirty-three studies were included and were categorized by mental health outcomes: anxiety/depression, emotional problems, total internalizing problems, total problem score, and conduct disorder. Over half of the analyses reported a positive association of prenatal alcohol exposure and offspring mental health problems.
Conclusions: Our review suggests that maternal alcohol use during pregnancy is associated with offspring mental health problems, even at low to moderate levels of alcohol use. Future investigation using methods that allow stronger causal inference is needed to further investigate if these associations shown are causal.
Prenatal alcohol use is associated with offspring mental health problems.
There is disparity in the measurement of internalising disorders across studies.
Future studies should utilise methods that allow stronger causal evidence.
|Domaine :||Alcool / Alcohol|
|Sous-type de document :||Revue de la littérature / Literature review|
|Affiliation :||UK Centre for Tobacco and Alcohol Studies, School of Psychological Science, University of Bristol, UK|