| Titre : | New trends in cannabis potency in USA and Europe during the last decade (2008-2017) (2019) |
| Auteurs : | S. CHANDRA ; M. M. RADWAN ; C. G. MAJUMDAR ; J. C. CHURCH ; T. P. FREEMAN ; M. A. ElSOHLY |
| Type de document : | Article : Périodique |
| Dans : | European Archives of Psychiatry and Clinical Neuroscience (Vol.269, n°1, February 2019) |
| Article en page(s) : | 5-15 |
| Langues: | Anglais |
| Discipline : | PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods) |
| Mots-clés : |
Thésaurus géographique ETATS-UNIS ; EUROPE ; FRANCE ; PAYS-BAS ; ITALIE ; ROYAUME-UNIThésaurus mots-clés CANNABIS ; TETRAHYDROCANNABINOL ; EVOLUTION ; ANALYSE CHIMIQUE ; MESURES QUANTITATIVES ; SURVEILLANCE EPIDEMIOLOGIQUE |
| Résumé : |
ENGLISH:
Through the potency monitoring program at the University of Mississippi supported by National Institute on Drug Abuse (NIDA), a total of 18108 samples of cannabis preparations have been analyzed over the last decade, using a validated GC/FID method. The samples are classified as sinsemilla, marijuana, ditchweed, hashish, and hash oil (now referred to as cannabis concentrate). The number of samples received over the last 5 years has decreased dramatically due to the legalization of marijuana either for medical or for recreational purposes in many US states. The results showed that the mean Delta9-THC concentration has increased dramatically over the last 10 years, from 8.9% in 2008 to 17.1% in 2017. The mean Delta9-THC:CBD ratio also rose substantially from 23 in 2008 to 104 in 2017. There was also marked increase in the proportion of hash oil samples (concentrates) seized (0.5-4.7%) and their mean Delta9-THC concentration (6.7-55.7%) from 2008 to 2017. Other potency monitoring programs are also present in several European countries such as The Netherlands, United Kingdom, France, and Italy. These programs have also documented increases in Delta9-THC concentrations and Delta9-THC:CBD ratios in cannabis. These trends in the last decade suggest that cannabis is becoming an increasingly harmful product in the USA and Europe. FRANÇAIS : Augmentation considérable de la concentration de THC dans le cannabis aux États-Unis et en Europe au cours des 10 dernières années. Aux États-Unis, les concentrations moyennes de THC dans le cannabis ont presque doublé en l'espace de 10 ans et sont passées de 9% en 2008 à 17% en 2017. Les concentrations de THC dans l'huile de haschisch ont également considérablement augmenté. D'autres programmes de surveillance de l'activité dans plusieurs pays Européens ont documenté des augmentations des concentrations de THC dans les produits à base de cannabis. [IACM, 12/02/2019] |
| Domaine : | Drogues illicites / Illicit drugs |
| Refs biblio. : | 60 |
| Affiliation : | National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS, USA |
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