|Titre :||Are patients' pejorative representations of buprenorphine associated with their level of addiction and of misuse? (2018)|
|Auteurs :||P. VANDERKAM ; S. GAGEY ; P. INGRAND ; M. C. PERAULT-POCHAT ; Y. BRABANT ; C. BLANCHARD ; B. TUDREJ ; N. MESSAADI ; P. BINDER|
|Type de document :||Article : Périodique|
|Dans :||Drug and Alcohol Dependence (Vol.188, July 2018)|
|Article en page(s) :||10-15|
|Discipline :||EPI (Epidémiologie / Epidemiology)|
Thésaurus TOXIBASEBUPRENORPHINE ; REPRESENTATION SOCIALE ; TRAITEMENT DE MAINTENANCE ; PHARMACIE ; ENQUETE ; USAGER
|Mots-clés:||princeps ; générique|
Background: In France, buprenorphine is at once the most widely prescribed and the most commonly misused opioid maintenance treatment (OMT). Unlike other medicines, it is seldom prescribed as a generic drug. Several studies have underlined the influence of the patient's representations when choosing brand-name rather than generic forms. We aim to prove a link between these pejorative representations and misuse, a higher degree of addiction and a preference for brand-name products.
Methods: An observational study carried out at 11 sites in France using self-assessment questionnaires filled out in dispensing pharmacies by patients having come to them for buprenorphine delivery.
Results: Analysis was based on 806 usable questionnaires. There indeed exists a significant correlation between pejorative representations of OMT by means of buprenorphine, and a higher degree of addiction and misuse (p Conclusion: Our results underscore the existence of a link between patients' negative representations of their OMT and their drug-taking behavior. Prescribing physicians should consequently take these representations into account to more precisely identify the relevant behaviors and help their patients to evolve positively.
|Domaine :||Autres substances / Other substances ; Drogues illicites / Illicit drugs|
|Affiliation :||Département de Médecine Générale, Faculté de Médecine, Poitiers, France|