Titre : | Alcohol use disorders and associated chronic disease - a national retrospective cohort study from France (2017) |
Auteurs : | M. SCHWARZINGER ; S. P. THIEBAUT ; S. BAILLOT ; V. MALLET ; J. REHM |
Type de document : | Article : Périodique |
Dans : | BMC Public Health (Vol.18, n°43, 2017) |
Article en page(s) : | 9 p. |
Langues: | Anglais |
Discipline : | EPI (Epidémiologie / Epidemiology) |
Mots-clés : |
Thésaurus géographique FRANCEThésaurus mots-clés ALCOOL ; PATHOLOGIE ORGANIQUE ; MORBIDITE ; FACTEUR DE RISQUE ; MORTALITE ; ETUDE RETROSPECTIVE ; AGE ; SEXE |
Résumé : |
BACKGROUND: Evidence on diseases caused by or associated with alcohol use disorders (AUDs) has been based on two meta-analyses including rather dated studies. The objective of this contribution was to estimate the risks of all-cause mortality and alcohol-attributable disease categories depending on a diagnosis of AUDs in a national sample for France.
METHODS: In a national retrospective cohort study on all inpatient acute and rehabilitation care patients in Metropolitan France 2008-2012 (N = 26,356,361), AUDs and other disease categories were identified from all discharge diagnoses according to standard definitions, and we relied on in-hospital death for mortality (57.4% of all deaths). RESULTS: 704,803 (2.7%) patients identified with AUDs had a threefold higher risk of death (HR = 2.98; 95% CI: 2.96-3.00) and died on average 12.2 years younger (men: 10.4, 95% CI: 10.3-10.5; women: 13.7, 95% CI: 13.6-13.9). AUDs were associated with significantly higher risks of hospital admission for all alcohol-attributable disease categories: digestive diseases, cancers (exception: breast cancer), cardiovascular diseases, dementia, infectious diseases, and injuries. Elevated risks were highest for liver diseases that were associated with about two-third of deaths in patients with AUDs (men: 64.3%; women: 71.1%). CONCLUSIONS: AUDs were associated with marked premature mortality and higher risks of alcohol-attributable disease categories. Our results support the urgent need of measures to reduce the burden of AUDs. |
Domaine : | Alcool / Alcohol |
Refs biblio. : | 51 |
Affiliation : | Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, ON, Canada |
Lien : | https://doi.org/10.1186/s12889-017-4587-y |
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