Historique
Article de Périodique
Hepatitis B virus in drug users in France: prevalence and vaccination history, ANRS-Coquelicot Survey 2011-2013 (2017)
Auteur(s) :
BROUARD, C. ;
PILLONEL, J. ;
SOGNI, P. ;
CHOLLET, A. ;
LAZARUS, J. V. ;
PASCAL, X. ;
BARIN, F. ;
JAUFFRET-ROUSTIDE, M.
Année :
2017
Page(s) :
1259-1269
Langue(s) :
Anglais
Domaine :
Drogues illicites / Illicit drugs
Discipline :
MAL (Maladies infectieuses / Infectious diseases)
Thésaurus géographique
FRANCE
Thésaurus mots-clés
ENQUETE
;
HEPATITE
;
PREVALENCE
;
VACCINATION
;
ETUDE TRANSVERSALE
;
DEPISTAGE
;
USAGER
;
INJECTION
;
PROFIL SOCIO-DEMOGRAPHIQUE
;
PRODUIT ILLICITE
;
CONDUITE A RISQUE
;
INFECTION
Résumé :
People who use drugs (PWUD) are a key population for hepatitis B virus (HBV) vaccination and screening. We aimed to estimate the seroprevalence of HBs antigen (HBsAg) and self-reported HBV vaccination history in French PWUD attending harm reduction centres using data from the ANRS-Coquelicot multicentre survey conducted in 2011-2013 in 1718 PWUD. Self-fingerprick blood samples were collected on dried blood spots to detect the presence of HBsAg. HBsAg seroprevalence was estimated at 1.4% [95% confidence interval (CI) 0.8-2.5]. It varied between PWUD born in high (7.6%, 95% CI 2.7-19.1), moderate (2.2%, 95% CI 0.8-5.7) and low (0.7%, 95% CI 0.3-1.5) endemic zones. Factors independently associated with HBsAg carriage were being born in a moderate or high endemic zone or reporting precarious housing. Self-reported HBV vaccination history varied from 47.4% in high endemic zones, to 59.3% and 62.6% for moderate and low endemic zones, respectively. Our results suggest that drug use plays a small and substantial role, respectively, in HBsAg carriage in PWUD born in high/moderate and low endemic zones.
Affiliation :
Santé publique France, Direction des Maladies Infectieuses, Saint-Maurice, France