| Titre : | 2C-I-NBOMe, an "N-bomb" that kills with "Smiles". Toxicological and legislative aspects (2015) |
| Auteurs : | P. NIKOLAOU ; I. PAPOUTSIS ; M. STEFANIDOU ; C. SPILIOPOULOU ; S. ATHANASELIS |
| Type de document : | Article : Périodique |
| Dans : | Drug and Chemical Toxicology (Vol.38, n°1, January 2015) |
| Article en page(s) : | 113-119 |
| Langues: | Anglais |
| Discipline : | PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods) |
| Mots-clés : |
Thésaurus TOXIBASE DROGUES DE SYNTHESE ; TOXICOLOGIE ; PHARMACOLOGIE ; LEGISLATION ; TYPE D'USAGE ; MECANISME D'ACTION ; EFFET SECONDAIRE ; INTOXICATION |
| Résumé : | Substituted phenethylamines are a class of designer drugs that have recently emerged in the drug abuse market. Such substances remain legal to use, possess, and supply until these compounds become classified as scheduled. 2C-I-NBOMe or 25I-NBOMe is the N-benzyl-derivative of the iodo-substituted dimethoxy-phenethylamine (2C-I) that appeared recently in the drug market under the street name "N-Bomb". Due to its high potency, intoxications and fatal cases related to 2C-I-NBOMe use are increased worldwide. The use and trafficking of this substituted phenethylamine is banned only in some countries. A comprehensive review was performed using PubMed and Medline databases, together with additional non-peer reviewed information sources, including books and publications of state authorities in different countries, regarding chemistry, availability, pharmacology, and toxicology of 2C-I-NBOMe. Intoxications or lethal cases, published or reported, as well as the current legislation on this newly introduced drug are also reviewed. |
| Domaine : | Drogues illicites / Illicit drugs |
| Sous-type de document : | Revue de la littérature / Literature review |
| Affiliation : | Faculty of Medicine, Department of Forensic Medicine and Toxicology, National and Kapodistrian University of Athens, Athens, Greece |
| Lien : | http://dx.doi.org/10.3109/01480545.2014.911882 |
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