Historique
Article de Périodique
2C-I-NBOMe, an "N-bomb" that kills with "Smiles". Toxicological and legislative aspects (2015)
Auteur(s) :
NIKOLAOU, P. ;
PAPOUTSIS, I. ;
STEFANIDOU, M. ;
SPILIOPOULOU, C. ;
ATHANASELIS, S.
Année :
2015
Page(s) :
113-119
Sous-type de document :
Revue de la littérature / Literature review
Langue(s) :
Anglais
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus mots-clés
DROGUES DE SYNTHESE
;
TOXICOLOGIE
;
PHARMACOLOGIE
;
LEGISLATION
;
TYPE D'USAGE
;
MECANISME D'ACTION
;
EFFET SECONDAIRE
;
INTOXICATION
Résumé :
Substituted phenethylamines are a class of designer drugs that have recently emerged in the drug abuse market. Such substances remain legal to use, possess, and supply until these compounds become classified as scheduled. 2C-I-NBOMe or 25I-NBOMe is the N-benzyl-derivative of the iodo-substituted dimethoxy-phenethylamine (2C-I) that appeared recently in the drug market under the street name "N-Bomb". Due to its high potency, intoxications and fatal cases related to 2C-I-NBOMe use are increased worldwide. The use and trafficking of this substituted phenethylamine is banned only in some countries. A comprehensive review was performed using PubMed and Medline databases, together with additional non-peer reviewed information sources, including books and publications of state authorities in different countries, regarding chemistry, availability, pharmacology, and toxicology of 2C-I-NBOMe. Intoxications or lethal cases, published or reported, as well as the current legislation on this newly introduced drug are also reviewed.
Affiliation :
Faculty of Medicine, Department of Forensic Medicine and Toxicology, National and Kapodistrian University of Athens, Athens, Greece