|Titre :||US federal cocaine essential ('precursor') chemical regulation impacts on US cocaine availability: an intervention time-series analysis with temporal replication (2015)|
|Auteurs :||J. K. CUNNINGHAM ; R. C. CALLAGHAN ; L. M. LIU|
|Type de document :||Article : Périodique|
|Dans :||Addiction (Vol.110, n°5, May 2015)|
|Article en page(s) :||805-820|
|Note générale :||Commentary: Essential chemical controls-miracle from a black box? Caulkins J., p. 821-822.|
|Discipline :||MAR (Marché de la drogue / Drug market)|
Thésaurus TOXIBASEREGULATION ; MARCHE DE LA DROGUE ; COCAINE ; PRIX ; PURETE ; REGLEMENTATION ; MODELE STATISTIQUE ; SAISIE ; PRECURSEURS ; DIFFUSION DES PRODUITS ; FABRICATION
Background and Aims: Research shows that essential/precursor chemical controls have had substantial impacts on US methamphetamine and heroin availability. This study examines whether US federal essential chemical regulations have impacted US cocaine seizure amount, price and purity-indicators of cocaine availability.
Design: Autoregressive integrated moving average (ARIMA)-intervention time-series analysis was used to assess the impacts of four US regulations targeting cocaine manufacturing chemicals: potassium permanganate/selected solvents, implemented October 1989 sulfuric acid/hydrochloric acid, implemented October 1992; methyl isobutyl ketone, implemented May 1995; and sodium permanganate, implemented December 2006. Of these chemicals, potassium permanganate and sodium permanganate are the most critical to cocaine production.
Setting: Conterminous United States (January 1987-April 2011).
Measurements: Monthly time-series: purity-adjusted cocaine seizure amount (in gross weight seizures Findings: The 1989 potassium permanganate/solvents regulation was associated with a seizure amount decrease (change in series level) of 28% (P Conclusions: In the United States, essential chemical controls from 1989 to 2006 were associated with pronounced downturns in cocaine availability.
|Domaine :||Drogues illicites / Illicit drugs|
|Refs biblio. :||72|
|Affiliation :||Department of Family and Community Medicine, The University of Arizona, Tucson, AZ, USA|
|URL :||Commentary: Essential chemical controls-miracle from a black box? Caulkins J., p. 821-822.|