Historique
Article de Périodique
25B-NBOMe and its precursor 2C-B: modern trends and hidden dangers (2015)
Auteur(s) :
PAPOUTSIS, I. ;
NIKOLAOU, P. ;
STEFANIDOU, M. ;
SPILIOPOULOU, C. ;
ATHANASELIS, S.
Année :
2015
Page(s) :
1-11
Langue(s) :
Anglais
Refs biblio. :
79
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus mots-clés
TOXICOLOGIE
;
DROGUES DE SYNTHESE
;
PHARMACOLOGIE
;
ANALYSE CHIMIQUE
;
PREVALENCE
;
TYPE D'USAGE
;
MECANISME D'ACTION
;
EFFET SECONDAIRE
;
INTOXICATION
;
ETUDE DE CAS
Résumé :
Substituted phenethylamines are a class of designer drugs that hold a significant position in the drug abuse market. The most important substances within this class appear to be 4-bromo-2,5-dimethoxyphenethylamine (2C-B) and its novel derivative 2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25B-NBOMe). Intoxications related to 2C-B use are still recorded worldwide, despite the fact that its use and trafficking are banned in many countries. 25B-NBOMe is a highly potent 2C-B derivative that has invaded recently in the "drug arena" and is considered legal to possess and supply in many countries. This manuscript reviews all available information regarding chemistry, availability, pharmacology, and toxicology of 2C-B and 25B-NBOMe. The intoxication and fatal cases reported, as well as the current legislation of these drugs, are also presented.
Affiliation :
Department of Forensic Medicine and Toxicology, Faculty of Medicine, National and Kapodistrian University of Athens, Athens, Greece