Titre : | Methadone deaths in Scotland (2015) |
Auteurs : | V. NIKOLAOU ; J. LUTY |
Type de document : | Article : Périodique |
Dans : | Heroin Addiction and Related Clinical Problems (Vol.17, n°1, March 2015) |
Article en page(s) : | 17-22 |
Langues: | Anglais |
Discipline : | EPI (Epidémiologie / Epidemiology) |
Mots-clés : |
Thésaurus géographique ECOSSE ; ROYAUME-UNIThésaurus mots-clés METHADONE ; PRODUIT DE SUBSTITUTION ; BUPRENORPHINE ; MORTALITE ; COUT |
Résumé : |
Aim: Identify factors which may be responsible for variations in methadone-related deaths in Scotland.
Method: Computer modelling based on data from drug-related deaths in Scotland in 2012 was used to predict the most effective combination of clinical parameters (methadone dose; supervision rates and provision of buprenorphine) that may predict how to reduce methadone-related deaths. Results: Doubling the proportion of patients receiving buprenorphine (from 12% to 24%) would reduce the overall death rate by 18% (from 7.58 to 6.20 deaths per thousand problem drug users ~82 deaths). This would cost an additional £2.52 million (£31 000 per life saved). Increasing the supervision rate for methadone from 57% to 67% would reduce the overall death rate by 0.68% (3 deaths ~£423 000 per life saved) while increasing the average daily dose of methadone from 90 mg to 100 mg would reduce the overall death rate by 2.5% (11 deaths ~£48 000 per life saved). Conclusion: Greater use of buprenorphine products could significantly reduce methadone-related deaths. |
Domaine : | Autres substances / Other substances |
Refs biblio. : | 18 |
Affiliation : | NHS Borders, Scotland, Borders Addiction Service, Galashiels, Scotland, UK, EU |
Lien : | http://www.heroinaddictionrelatedclinicalproblems.org/harcp-archives.php |
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