|Titre :||Cost-effectiveness of injectable opioid treatment v. oral methadone for chronic heroin addiction (2013)|
|Auteurs :||S. BYFORD ; B. BARRETT ; N. METREBIAN ; T. GROSHKOVA ; M. CARY ; V. CHARLES ; N. LINTZERIS ; J. STRANG|
|Type de document :||Article : Périodique|
|Dans :||British Journal of Psychiatry (Vol.203, n°5, November 2013)|
|Article en page(s) :||341-349|
|Note générale :||Editorial: Injectable heroin - effective treatment for opiate misusers, but is it cost-effective? Hunter R.M., Hasan S., p. 325-326.|
|Discipline :||TRA (Traitement et prise en charge / Treatment and care)|
Thésaurus TOXIBASEHEROINE ; COUT ; EFFICACITE ; INJECTION ; METHADONE ; COMPARAISON ; DISTRIBUTION CONTROLEE ; TRAITEMENT DE MAINTENANCE ; ETUDE CLINIQUE ; ETUDE RANDOMISEE
Background: Despite evidence of the effectiveness of injectable opioid treatment compared with oral methadone for chronic heroin addiction, the additional cost of injectable treatment is considerable, and cost-effectiveness uncertain.
Aims: To compare the cost-effectiveness of supervised injectable heroin and injectable methadone with optimised oral methadone for chronic refractory heroin addiction.
Method: Multisite, open-label, randomised controlled trial. Outcomes were assessed in terms of quality-adjusted life-years (QALYs). Economic perspective included health, social services and criminal justice resources.
Results: Intervention costs over 26 weeks were significantly higher for injectable heroin (mean £8995 v. £4674 injectable methadone and £2596 oral methadone; P Conclusions: Injectable opioid treatments are more cost-effective than optimised oral methadone for chronic refractory heroin addiction. The choice between supervised injectable heroin and injectable methadone is less clear. There is currently evidence to suggest superior effectiveness of injectable heroin but at a cost that policy makers may find unacceptable. Future research should consider the use of decision analytic techniques to model expected costs and benefits of the treatments over the longer term.
|Domaine :||Drogues illicites / Illicit drugs|
|Refs biblio. :||34|
|Affiliation :||Centre for the Economics of Mental and Physical Health, Institute of Psychiatry, King's College London, UK|